نتایج جستجو برای: anticardiolipin antibody
تعداد نتایج: 167940 فیلتر نتایج به سال:
BACKGROUND The mechanism underlying Buerger's disease (BD) is still unknown. Recently, thrombophilic conditions predisposing to a hypercoagulable state have been hypothesized as triggers for BD. The aim of the study is to evaluate the prevalence of the hyperhomocysteinemia and level of the anticardiolipin antibodies, and the role of folic acid on the hyperhomocysteinemia and on the rate of the ...
Background: Graves’ disease is an autoimmune disease, characterized by the presence of antibodies directed to TSH receptor or nearby regions as well as antibodies to double strands DNA (dsDNA) anticardiolipin and nuclear antibodies. This study evaluated anticardiolipin and rheumatoid factor, such as IgA and IgM antibodies in patients with Graves’ disease. Patients and methods: Anticardiolipin a...
A child showing signs of Henoch-Schönlein purpura developed a right tibiofibular vascular thrombosis. Antiphospholipid antibody tests were positive for both lupus anticoagulant and anticardiolipin antibodies. This suggests that an antiphospholipid syndrome should be considered in cases of Henoch-Schönlein purpura and antiphospholipid antibodies should be measured to determine whether prophylact...
Laboratory diagnosis of APS relies on the demonstration of positive antiphospholipid antibodies (aPL), including anticardiolipin antibody (aCL) and/or anti2 glycoprotein I antibody (anti2GPI) by an in-house or commercially available enzyme-linked immunosorbent assay (ELISA) or lupus anticoagulant (LA) by a coagulation-based test. The relationship between aPL and thrombosis has been abundantly s...
BACKGROUND To our knowledge, the contribution of prothrombotic conditions to cerebral thromboembolism has never been prospectively studied in a large series of pediatric patients. METHODS The Hospital for Sick Children, Toronto, Ontario, established a program in January 1992 to diagnose and treat children (term newborn to 18 years old) with arterial ischemic stroke or sinovenous thrombosis. T...
Antiphospholipid syndrome (APS) is typically characterized by increased levels of three classes antiphospholipid antibodies, namely lupus anticoagulant, anti-β2-glycoprotein I (anti-β2GPI), and anticardiolipin antibodies. β2-Glycoprotein (β2GPI) a phospholipid-binding protein composed five domains (DI–V) major antigen in APS. β2GPI expressed on the surfaces several cell types, including endothe...
Background and Purpose: The most common complication of pregnancy is abortion. The etiology of recurrent pregnancy loss is not completely known. There are few therapeutics and diagnostic strategies in recurrent abortion. The aim of this study was to compare the use of heparin with aspirin vs prednisolone with aspirin in patients with recurrent pregnancy loss (RPL). Materials and Methods: T...
BACKGROUND Congenital or acquired prothrombin deficiency is a rare condition. CASE REPORT A 2-year-7-month old Thai girl presented with ecchymosis, bleeding at both thighs and right ear lobe after a self-limited viral infection. RESULTS The investigations revealed prolonged APTT and PT, prothrombin level 6% and positive anticardiolipin antibody 26.2 IU/mL. The 1:1 mixture of her plasma and ...
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