نتایج جستجو برای: anticancer drugs

تعداد نتایج: 252007  

2013
Hsin-chung Lee Qing-Dong Ling Wan-Chun Yu Chunh-Ming Hung Ta-Chun Kao Yi-Wei Huang Akon Higuchi

PURPOSE We evaluated the higher levels of carcinoembryonic antigen (CEA) secreted by the LoVo human colon carcinoma cells in a medium containing anticancer drugs. Drug-resistant LoVo cells were analyzed by subcutaneously xenotransplanting them into mice. The aim of this study was to evaluate whether the drug-resistant cells isolated in this study were cancer-initiating cells, known also as canc...

2012
Juan Sebastian Yakisich

The anticancer drugs screening program is a long and expensive process. It is estimated that only 5% of drugs entering clinical trials are approved by the FDA. Moreover, many of the drugs that enter clinical trials are often of limited use in clinical practice, and most cancers remain untreatable. Brain tumors are particularly difficult to treat due to the presence of the blood brain barrier th...

2014
Joong Sup Shim Jun O. Liu

Drug repositioning (also referred to as drug repurposing), the process of finding new uses of existing drugs, has been gaining popularity in recent years. The availability of several established clinical drug libraries and rapid advances in disease biology, genomics and bioinformatics has accelerated the pace of both activity-based and in silico drug repositioning. Drug repositioning has attrac...

Journal: :Journal of Clinical Pharmacy and Therapeutics 2001

Journal: :Acta Scientific Medical Sciences 2019

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