Pseudomonas aeruginosa is one of the most important pathogens that causes nosocomial infections and shows high level of antibiotic resistance. Integrons are one of the transposable elements in bacteria and their role in antibiotic resistance has been well demonstrated. The aim of this study was a molecular characterization of the integron genes and the determination of the resistance or sensiti...

patients and methods two-hundred and fifty-five clinical specimens were collected from four major provinces of iran. samples were cultured and the mrsa strains were subjected to polymerase chain reaction (pcr). the patterns of antibiotic resistance were determined using the disk diffusion method. results seventy-four out of 255 (29.01%) clinical samples were positive for mrsa. of the 74 mrsa st...

Antibiotic abuse can lead to antibiotic resistance, which is a severe problem in China. The purpose of this study is to evaluate the short-term effects of antimicrobial stewardship strategies, including formulary restriction, preauthorization, perioperative quinolone restriction, and control of total antibiotic consumption in the ICU at a tertiary hospital in China. After implementation of anti...

There are two general approaches to preventing or reversing antimicrobial resistance in the hospital setting. Prevention of transmission of resistant organisms from patient to patient is the traditional infection control approach that, if practiced perfectly, would resolve the problem of nosocomial infection due to resistant .organisms. It is the stuff of which all good hospital epidemiologists...

Introduction: Antibiotics are one of the key discoveries in human history. Unfortunately, global rise antimicrobial drug resistance has become most pressing medical problems. Monitoring antibiotic consumption is important components all programs aimed at controlling problem with rising resistance. Aim: The aim this article to present a free and internationally standardized electronic-based meth...

Bacterial infections can be serious and require antibiotic treatment. However, the overuse of antibiotics has led to development antibacterial resistance, which make more difficult treat. This is a problem in Mexico, where published research on resistance limited. study aimed estimate prevalence bacterial at Hospital General del Estado Hermosillo, Mexico. Information was collected from 2,205 bi...

BACKGROUND Antibiotic resistance in bacterial infections is a growing threat to public health. Recent evidence shows that when exposed to stressful conditions, some bacteria perform higher rates of horizontal gene transfer and mutation, and thus acquire antibiotic resistance more rapidly. METHODS We incorporate this new notion into a mathematical model for the emergence of antibiotic multi-re...

Methicillin-resistant Staphylococcus aureus (MRSA) isolates came into existence soon after the introduction of methicillin. Historically, MRSA isolates have been associated with nosocomial infections and rapidly developed resistance to multiple drug classes. However, in recent years, different strains with unique phenotypes have emerged in the community, and the reservoir of community-associate...

Integrons are genetic elements that contribute to lateral gene transfer in bacteria as a consequence of possessing a site-specific recombination system. This system facilitates the spread of genes when they are part of mobile cassettes. Most integrons are contained within chromosomes and are confined to specific bacterial lineages. However, this is not the case for class 1 integrons, which were...