BACKGROUND The purpose of this scoping review was to review the literature on healthcare provider provision of anti-D prophylaxis to RhD negative pregnant women in appropriate clinical situations in various healthcare settings. METHODS A scoping review framework was used to structure the process. The following databases were searched: CINAHL (EBSCO), EBM Reviews (OvidSP), Embase (OvidSP), Med...

We have studied the evolution of hepatitis C virus (HCV) from a common source following serial transmission from contaminated batches of anti-D immunoglobulin. Six secondary recipients were each infected with virus from identifiable primary recipients of HCV-contaminated anti-D immunoglobulin. Phylogenetic analysis of virus E1/E2 gene sequences [including the hypervariable region (HVR)] and par...

접수 : 2007년 12월 4일, 승인 : 2008년 1월 9일 책임저자 : 임영탁, 부산대학교 의과대학 소아과학교실 Correspondence : Young Tak Lim, M.D. Tel : 051)240-7298 Fax : 051)248-6205 E-mail : [email protected] 의한다고 알려져 있으며, 자가 항체가 붙은 혈소판이 비장이나 다른 망상내피계에 있는 탐식세포에 의해 조기 파괴되어 일어나 게 된다 1-3) . ITP 환아들은 비교적 양성 경과를 취하지만 혈소판 수치가 20,000/μL 이하로 혈소판 감소 정도가 심한 경우에는 두 개내 출혈과 같은 위중한 합병증을 초래할 수 있으므로 발병 수 일 내에 혈소판수를 정상으로 회복시켜 주는 것이 중요하다 4-6) . ITP의 치료...

Coronavirus disease 2019 mass vaccination has led to drastic reduction in hospitalizations and mortality. A number of case reports have emerged reporting coronavirus infection within days following vaccination. There is a need understand development immune antibodies the early post-vaccination period. prospective analysis immunoglobulin M G kinetics was conducted during first 28 d with either C...

BACKGROUND Anti-D monoclonal antibody (MoAb) reagents have improved D typing in routine tests. However, they exhibit a wide range of reactivity with the weak D phenotype depending on the characteristics of the different MoAbs used. We analyzed the reactivity of immunoglobulin (IgM) anti-D by cluster analysis to characterize MoAb that have similar reactivities with the weak D phenotype. STUDY ...

Five patients treated with intraperitoneal 131I-labeled mouse monoclonal antibody for ovarian cancer also received i.v. exogenous polyclonal human anti-murine immunoglobulin antibody. The pharmacokinetics of 131I-labeled monoclonal antibody in these patients were compared with those of 28 other patients receiving i.p.-radiolabeled monoclonal antibody for the first time without exogenous human a...

Of 655 Rh negative women without anti-D antibody in their serum at genetic amniocentesis, 361 delivered a Rh positive infant. Prophylactic treatment with anti-D immunoglobulin was not given at amniocentesis. The women were followed prospectively, being given a screening test for antibody after amniocentesis, at delivery, and six months later. Five of these 361 women yielded a positive test resu...

recently it has been reported, that immunoglobulin y (igy) can be used instead of polyclonal antibodies extracted from mammals (igg) for the purpose of diagnosis and therapy. these antibodies are found to have better properties in terms of specificity and ease of large-scale production. in addition, igy binds neither to mammalian complement or fc-receptors nor does it interfere with rheumatoid ...