background: cutaneous leishmaniasis (cl) caused by leishmania tropica is endemic in kerman, southeastern iran. while dogs have long been implicated as the main domestic reservoirs of l. infantum , etiological agent of zoonotic visceral leishmaniasis (zvl), they can also carry l. tropica infection. the objective of the present study was to determine molecular identity and to evaluate histopathol...

In the past decade, the number of imported leishmaniasis cases has increased in countries of Western Europe. The trend is associated with increasing travels, ecotourism activity, military operations and immigration. While in endemic countries leishmaniasis is usually well diagnosed, accurate patient history and parasite identification are necessary to distinguish between autochthonous and impor...

Leishmaniasis is an infectious disease caused by protozoa of the genus Leishmania transmitted by insects of the genus Lutzomyia sp. or Phlebotomus sp. The main syndromes are cutaneous leishmaniasis, mucocutaneous leishmaniasis, visceral leishmaniasis (kala-azar) and post-kala-azar dermal leishmaniasis. This article reviews kidney involvement in cutaneous and visceral leishmaniasis, highlighting...

Background Establishment of sand flies laboratory colonies is essential to understand various biological aspects of Phlebotominae sand flies. The aims of the current study were to establish the colony of Phlebotomus sergenti Parrot (1917), the main vector of anthroponotic cutaneous leishmaniasis in old world, and to study biological parameters of this species. Methods The sand flies were rear...

Identification of Cutaneous Leishmaniasis-causing Species Using Semi-Nested PCR in Kohgiluyeh and Boyer-Ahmad Province During 2013-2019

conclusions according to the epidemiological features of cl in iran, providing a uniform mechanism for control and prevention of this disease is not possible. thus, initial actions such as staff training, screening in endemic areas, and treatment of patients with urban leishmaniasis as a reservoir for the disease can be useful, according to the geographical position and carrier. results most of...

The wide variety of Leishmania species responsible for human American cutaneous leishmaniasis combined with the immune mechanisms of the host results in a large spectrum of clinical, histopathological, and immunopathological manifestations. At the middle of this spectrum are the most frequent cases of localized cutaneous leishmaniasis (LCL) caused by members of the subgenera Leishmania and Vian...

Leishmaniasis is endemic in 88 countries throughout Africa, Asia, Europe and North and South America (Dedet et al., 2003). There are an estimated 12 million cases worldwide and there are about 1.5 million new cases of cutaneous leishmaniasis (CL) each year of which over 90% occur in Afghanistan, Algeria, Iran, Iraq, Saudi Arabia, Syria, Brazil and Peru (Ashford et al., 1992). Old World disease ...

Pentavalent antimonial compounds have been the first line therapy for leishmaniasis; unfortunately the rate of treatment failure of anthroponotic cutaneous leishmaniasis (ACL) is increasing due to emerging of drug resistance. Elucidation of the molecular mechanisms operating in antimony resistance is critical for development of new strategies for treatment. Here, we used a cDNA-AFLP approach to...

Introduction: Cutaneous leishmaniasis can lead to the loss of time, labor force, significant treatment costs and psychological problems. Also, cutaneous leishmaniasis is considered as an important health problem in Iran. This study was aimed to investigat the status of cutaneous leishmaniasis in Dashtestan district. Materials and Methods: This cross-sectional and descriptive-correlational...