In this study, it was aimed to provide biocontrol of Salmonella spp. and Listeria contamination in tahini. For purpose, 10 different tahini samples were obtained from Kahramanmaraş market enumeration spp., total mesophilic aerobic bacteria (TMAB), yeast-mold, Staphylococcus coliform made. Antagonistic effects Lactiplantibacillus plantarum CompaniLactobacillus alimentarius strains against typhim...

A 25-carboxylic ester analog of 1alpha,25-dihydroxyvitamin D(3) [1alpha,25(OH)(2)D(3)], ZK159222 (compound 1), was recently described as a novel type of antagonist of 1alpha,25(OH)(2)D(3) signaling. In this study five derivatives of compound 1 (compounds 2-6) were selected because of their sensitivity in facilitating complex formation between the 1alpha,25(OH)(2)D(3) receptor (VDR) and the reti...

STUDY DESIGN Lifting dynamics and electromyographic activity were evaluated using a biomechanical model of spinal equilibrium and stability to assess cost-benefit effects of antagonistic muscle cocontraction on the risk of stability failure. OBJECTIVES To evaluate whether increased biomechanical stability associated with antagonistic cocontraction was capable of stabilizing the related increa...

Docetaxel (DOC) plus cisplatin (CDDP) is a novel combination chemotherapy for the treatment of advanced non-small-cell lung cancer (NSCLC). We investigated the combined effect of DOC with CDDP in sequence and the reverse schedule for NSCLC cell lines EBC-1 (squamous cell carcinoma) and RERF-LC-MS (adenocarcinoma) using an MTT assay and an improved isobologram method. The results showed that the...

Mutation generates a steady supply of genetic variation that, while occasionally useful for adaptation, is more often deleterious for fitness. Recent research has emphasized that the fitness effects of mutations often differ between the sexes, leading to important evolutionary consequences for the maintenance of genetic variation and long-term population viability. Some forms of sex-specific se...

the most common pathogenic agent in sunflower is sclerotinia sclerotiorum which in some cases can be successfully controlled by some antagonistic bacteria. environmental factors such as carbon sources are effective on antagonistic strains but application of pure carbohydrates for mass production of these agents is expensive. so in most cases agricultural and industrial residues (such as molasse...

Inflammation plays a key role in the development of proliferative vitreoretinopathy (PVR). This study aimed to detect the effects of bradykinin (BK) on retinal pigment epithelium (RPE) cells, especially regarding inflammation and collagen formation, and to investigate the possible pathway, including the receptors and downstream molecules. We found that BK induced an increase in Ca2+ and the lev...

Combinatorial chemopreventive strategies, in contrast to those with individual agents, show potential in terms of potentially lower toxicity and higher efficacy. In this study, we combined several agents and examined their suppressive effects on the combined lipopolysaccharide (LPS)- and interferon(IFN)-gamma-induced formation of proinflammatory mediators, including prostaglandin (PG) E2 and tu...

Phospholipase A2 (Pla2) is an enzyme that induces inflammation, making Pla2 activity an effective approach to reduce inflammation. Therefore, investigating natural compounds for this Pla2 inhibitory activity has important therapeutic potential. The objective of this study was to investigate the potential in bromelain-phytochemical complex inhibitors via a combination of in silico and in vitro m...