Replacement of deficient hormones is an important axis of anti-aging medicine since aging is caused and manifested by various hormonal declines. Somatopause has been treated with growth hormone; andropause with testosterone; thyropause with thyroid hormones; and menopause with estrogen or other natural substances (including isoflavone and black cohosh), whereas facial flush, genital atrophy and...

© Translational Andrology and Urology. All rights reserved. Transl Androl Urol, 2015;4(S1) www.amepc.org/tau and epididymides from rats in all groups were removed, weighed and subjected to histological examination and semen analysis after treatment. Oxidative stress was assessed by measuring 8-hydroxy-20-deoxyguanosine (8-OHdG) and superoxide dismutase (SOD). Results: The results showed that KH...

Interest has arisen during the last 10 years as to the possible connection between the age-related decline in androgen production and symptoms of ageing in men. A new ageing-related syndrome with several descriptive names, such as andropause, male menopause, Partial Androgen Deficiency of the Ageing Male (PADAM) and Late-Onset Hypogonadism (LOH), has been identified. Intensive research into the...

Androgens play a number of important physiological roles in the human. In the male, testosterone is required for virilization, normal sexual function, and both stimulation and maintenance of bone and muscle mass. Epidemiological studies have shown a progressive decline in testosterone levels with ageing in men. The clinical significance of this decline is still unclear, and there is controversy...

© Translational Andrology and Urology. All rights reserved. Transl Androl Urol, 2015;4(S1) www.amepc.org/tau and epididymides from rats in all groups were removed, weighed and subjected to histological examination and semen analysis after treatment. Oxidative stress was assessed by measuring 8-hydroxy-20-deoxyguanosine (8-OHdG) and superoxide dismutase (SOD). Results: The results showed that KH...

BACKGROUND In 1889, Brown-Séquard, aged 72, reported dramatic rejuvenating effects after self-administering testicular extracts of dogs and guinea-pigs. His report resulted in widespread use of testicular extracts throughout Europe and North America for several decades. More recently, the male ageing process has been attributed to partial androgen deficiency, or "andropause", and testosterone t...

While there is ample experimental evidence supporting the role of estrogen in the pathogenesis of Alzheimer disease, recent inconclusive data regarding hormone replacement therapy (HRT), specifically, the unexpected results of the Women's Health Initiative (WHI) Memory Study has raised serious questions regarding the protective effects of estrogen. Because of this and other inconsistencies in t...