background: in recent years concerns have been raised about human reproductive disorders, specially the effects of environmental factors on human fertility and pregnancy outcome. therefore, the present study was designed to assess the effects of maternal caffeine consumption on ovarian follicles development in rat offspring. methods: 60 pregnant female rats were randomly divided into a control ...

Abstract Robusta beans have a bitter taste, sour and high caffeine content. coffee contains 2.2 percent caffeine, while Arabica 1.2 caffeine. The level in the can be lowered through decaffeinated process. Optimal extraction from requires heating via However, temperatures long times reduce flavor due to degradation of flavor-forming compounds, resulting with weak flavor. This research aimed enha...

background and aim: caffeine at low doses blocks adenosine receptors. these receptors are present in all parts of the body including auditory and vestibular system. this study aimed to evaluate the effects of caffeine on cervical vestibular evoked myogenic potential (cvemp). methods: in this interventional double-blind study, 40 cases (20 females and 20 males) aged 18-25 years were randomly ass...

This study compared caffeine pharmacokinetics, glycerol concentrations, metabolic rate, and performance measures following ingestion of a time-release caffeine containing supplement (TR-CAF) versus a regular caffeine capsule (CAF) and a placebo (PL). Following a double-blind, placebo-controlled, randomized, cross-over design, ten males (25.9 ± 3.2 y) who regularly consume caffeine ingested caps...

1. Abstract 2. Introduction 3. N-methyltransferases involved in caffeine biosynthesis 3.1. N-methyltransferase activity in cell free preparations 3.2. Purification of caffeine synthase from tea leaves 3.3. Molecular cloning of caffeine synthase gene from tea leaves 3.4. The orthologous genes in coffee 3.5. The characteristic future of N-methyltransferase in theobromineaccumulating species 4. Ca...

Background: Sigma receptors, N-methyl-D-aspartate (NMDA) antagonist, and modulators of intracellular calcium may be useful for seizure control. Therefore, we aimed to evaluate the antiepileptic effects of opipramol, a sigma receptor agonist, against pentylenetetrazole (PTZ)-induced seizures in mice and assess ketamine and caffeine interaction with the antiepileptic effects of opipramol.Methods:...

Serum and milk concentrations of caffeine were measured in 5 breast-feeding mothers after a standardised oral dose of caffeine. Peak concentrations of caffeine in serum and milk were attained 60 minutes later. Binding of caffeine by constituents of serum and breast milk was low (25 and 3.2% respectively). In breast milk, caffeine binding is associated with the cream layer, and correlates with t...

low calorie diets are always difficult for obese subjects to follow and lead to metabolic and behavioral adaptation. therefore, we evaluated the effect of caffeine treatment with calorie shifting diet (csd) on weight loss. female subjects (n=98; bmi≥25) completed 4-weeks control diet, 6-weeks csd (3 repeated phases; each 2-weeks) and 4-weeks follow-up diet, with or without caffeine treatment (5...