T cell tolerance to parenchymal self-antigens is thought to be induced by encounter of the T cell with its cognate peptide-major histocompatibility complex (MHC) ligand expressed on the parenchymal cell, which lacks appropriate costimulatory function. We have used a model system in which naive T cell receptor (TCR) transgenic hemagglutinin (HA)-specific CD4+ T cells are adoptively transferred i...

Low soil fertility and high weed infestation are the main culprits for the declining maize production inWestern Kenya. Technology packages to address these constraints exist, but their effectiveness is likely to be influenced by variability in soil types and farm management practices in the region. Trials were conducted during the 2008/2009 cropping seasons to investigate the nutrient use e...

Among the single treatments tested under in vivo addition of well decomposed FYM 20 tons per hectare as soil amendment recorded minimum wilt incidence of 3.75, 24.76 and 48.25 % at flowering, fruit formation and ripening stages of chilli crop, respectively, with 61.31 q ha fruit yield as compared to check (42.50 q ha). Dual application of Trichoderma viride 0.16 t ha + FYM 20 t ha recorded mini...

A two-year dry season experiment was conducted at the research farm of the International Institute of Tropical Agriculture, IITA Ibadan, Nigeria to estimate irrigation water requirements and establish crop water use. Two upland rice varieties (NERICA 2 and NERICA 4) were planted in a randomized complete block design (RCBD). Four treatments based on different water distribution levels were adopt...

The purposes of this study are to characterize the binding of hyaluronic acid (HA) to mouse T lymphoma cells, to measure changes in intracellular Ca2+ after HA binding, to elucidate the interaction between the HA receptor, GP85(CD44), and ankyrin in the membrane skeleton, and finally to correlate these events with HA receptor patching/capping and cell adhesion to HA. First, we established an in...