syndrome in extensive haemangioma of the tongue and lip in a newborn infant.4 Thirdly, the substernal goitres reported in the literature have not been uniformly defined in relation to the proportion of the thyroid gland within the thorax. Therefore, it is rather difficult to compare the sizes and the results of reported series of substernal goitres. For the last decade, we and others' have chos...

syndrome in extensive haemangioma of the tongue and lip in a newborn infant.4 Thirdly, the substernal goitres reported in the literature have not been uniformly defined in relation to the proportion of the thyroid gland within the thorax. Therefore, it is rather difficult to compare the sizes and the results of reported series of substernal goitres. For the last decade, we and others' have chos...

A 51-year-old man with a history of unstable angina was scheduled for CABG surgery. He had no history of a prior general anesthetic or allergies. He sustained a Q-wave inferior myocardial infarction 12 years ago, and his ejection fraction was 54%. Current medications were nisoldipine, 5 mg, a calcium channel blocker; celiprolol, 200 mg, a P-blocker; and m&dine, 150 mg, as well as a continuous i...

Anaphylactic reactions in the peri-operative period are often serious and potentially life-threatening conditions, involving multiple organ systems in which the clinical manifestations are the consequence of the release of preformed mediators from mast cells and basophils. Anaphylaxis is an immune mediated type I allergic reaction following the massive release of mediators from mast cells and b...

1. Severe anaphylactoid reactions have been reported in some patients treated with angiotensin converting enzyme (ACE) inhibitors during hemodialysis with a polyacrylonitrile (PAN) membrane. Generation of bradykinin via contact activation at the negatively charged membrane surface and reduced bradykinin breakdown due to ACE inhibition have been suggested as possible causes. This hypothesis was ...