1. The polysaccharide fractions from each of five yeast-like fungi produce rapid, fatal anaphylactic shock in guinea pigs passively sensitized with antiserum from rabbits immunized against the killed organisms. 2. Cross-anaphylactic reactions with heterologous polysaccharide fractions are frequent. They parallel closely the cross-precipitin reactions, thus adding evidence in favor of the identi...

Shock as an inadequate tissue perfusion is one of the frequent causes of death in trauma patients. In this context, there are various reasons for hemodynamic instability and shock including hypovolemic (hemorrhagic), obstructive (cardiac tamponade, tension pneumothorax), cardiogenic, neurogenic, and rarely septic. In the present report, a 30-year-old trauma patient with full clinical signs and ...

tion of the cardiopulmonary changes observed during anaphylactic shock. The two subjects with the most severe shock showed evidence of intravascular coagulation characterized by a diminution of Factor V, Factor VIII, fibrinogen, and high molecular weight kininogen, as well as changes in components of the complement system. Standard therapy with epinephrine and fluids, usually recommended for th...

We report the proper management of a severe adverse reaction of anaphylactic shock during intravenous fluorescein angiography at an outpatient clinic. A 72-year-old male developed the severe, life-threatening complication after intravenous injection of sodium fluorescein dye for retinal angiography. Three minutes after receiving an intravenous injection of fluorescein, the patient developed syn...

*Supported in part by the Mr. and Mrs. F. H. Tewksbury grant administered by the San Diego Bio-Chemical Research Institute. 3-13-64 electrocardiographic changes in antigenantibody reactions have been described.34 Electrocardiographic observations of near fatal anaphylactic reactions in the human are sparse. In anaphylactic shock, the most dread of all allergic manifestations, widespread histami...

tion of the cardiopulmonary changes observed during anaphylactic shock. The two subjects with the most severe shock showed evidence of intravascular coagulation characterized by a diminution of Factor V, Factor VIII, fibrinogen, and high molecular weight kininogen, as well as changes in components of the complement system. Standard therapy with epinephrine and fluids, usually recommended for th...

Drug therapies grow more complex, thus a wide range of drug-related problems (DRPs) may arise. Adverse drug reactions (ADRs) are responsible for approximately 10% of all DRPs. The most severe form of ADR is an anaphylactic shock. It is estimated that severe anaphylaxis affects annually 1–3 per 10 000 people and causes death of 0.65–2% of those patients, i.e. 1–3 per 1 000 000 people. Fatal drug...