The contribution of order alpha(2)(Zalpha)(6)ln (3)(Zalpha)(-2) to the ground-state Lamb shift in hydrogen induced by the loop-after-loop diagram is evaluated analytically. An additional contribution of this order is found compared to the previous calculation by Karshenboim [Sov. Phys. JETP 76, 541 (1993)]. As a result, agreement is achieved for this correction between different numerical and a...

The laboratory preparation of peptides, once a challenge, is now a standard operation that can be automatised. However, the need for particular protecting groups requiring relatively harsh conditions for their removal (strong acids or bases) and reactive coupling agents can be problematic in specific cases (e.g. in a cell or in a microfluidic device). In this account, we describe our efforts to...

In today’s competitive educational environment, the quality of undergraduate education is ever more recognised as a fundamental factor in gaining competitive advantage. The evaluation and improvement of the quality of undergraduate education in higher education is an important issue of on-going concern. The aim of this article is to focus on an automated management and evaluation system to effi...

Genome-wide association studies raise study-design and analytical issues that are still being debated. Among them, stands the issue of reducing the number of markers to be genotyped without loss of efficiency in identifying trait loci, which can reduce the cost of studies and minimize the multiple testing problem. With this aim, we proposed a two-step strategy based on two analytical methods su...

Rare variants are becoming the new candidates in the search for genetic variants that predispose individuals to a phenotype of interest. Their low prevalence in a population requires the development of dedicated detection and analytical methods. A family-based approach could greatly enhance their detection and interpretation because rare variants are nearly family specific. In this report, we t...

Supplier selection is an important issue in supply chain management (SCM), and essentially is a multi-criteria decision-making problem. Supplier selection highly depends on experts’ assessments. In the process of that, it inevitably involves various types of uncertainty such as imprecision, fuzziness and incompleteness due to the inability of human being’s subjective judgment. However, the exis...

A microfluidic passive valving platform is introduced that has full control over the stability of each valve. The concept is based on phaseguides, which are small ridges at the bottom of a channel acting as pinning barriers. It is shown that the angle between the phaseguide and the channel sidewall is a measure of the stability of the phaseguide. The relationship between the phaseguide-wall ang...

The aim of this study is to provide an analytical tool to select the best software providing the most customer satisfaction. The three type of softwares were examined and the most important criterias were taken into account by the customers while they were selecting their softwares. The fuzzy analytic hierarchy process was used to compare this softwares. The means of the triangular fuzzy number...

#National Centre for Macromolecular Hydrodynamics, Department of Biochemistry, Leicester University, University Road, Leicester, LEI1 7RH, UK. +MRC Cellular Immunology Unit, Sir William Dunn School of pathology, University of Oxford, Oxford, OX I 3RE, UK. National Centre for Macromolecular Hydrodynamics, Department of Applied Biochemistry and Food Science, Nottingham University, Sutton Boningto...

Potential utilization of proteins for early detection and diagnosis of various diseases has drawn considerable interest in the development of protein-based multiplex detection techniques. Among the various techniques for high-throughput protein screening, optically-encoded beads combined with fluorescence-based target monitoring have great advantages over the planar array-based multiplexing ass...