نتایج جستجو برای: amphiphiles

تعداد نتایج: 1255  

Journal: :Chemical communications 2010
Luke C Henderson Jian Li Roger L Nation Tony Velkov Frederick M Pfeffer

New structural amphiphiles 2a and 2b bind the diphosphate lipid A anion and show potential as lead compounds for the development of novel antibacterial agents.

Journal: :Chemical communications 2008
Jeroen van Herrikhuyzen Giuseppe Portale Jeroen C Gielen Peter C M Christianen Nico A J M Sommerdijk Stefan C J Meskers Albertus P H J Schenning

Janus gold nanoparticles are synthesised via a simple preparation method and behave as amphiphiles self-assembling in water into disk-shaped micelles.

Journal: :Chemical communications 2008
Kyung-Soo Moon Eunji Lee Myongsoo Lee

Propeller-shaped aromatic amphiphiles based on a conformationally flexible aromatic segment are shown to self-assemble into well-defined discrete nanostructures with high fluorescence characteristic.

Journal: :Chemical communications 2008
Barbora Brazdova Ningrong Zhang Vyacheslav V Samoshin Xin Guo

Protonation-induced conformational change of lipid tails is reported as a novel strategy to render pH-sensitive lipid amphiphiles and lipid colloids.

Journal: :Chemical communications 2008
Samuel D Whitmarsh Adrian P Redmond Valentina Sgarlata Anthony P Davis

Cholic acid has been transformed into cyclotrimeric and cyclotetrameric toroidal amphiphiles with inward-directed ammonium substituents; the cyclotrimer effects the transport of chloride anions across vesicle bilayer membranes.

Journal: :Chemical communications 2005
A J Ton Dirks Sander S van Berkel Nikos S Hatzakis Joost A Opsteen Floris L van Delft Jeroen J L M Cornelissen Alan E Rowan Jan C M van Hest Floris P J T Rutjes Roeland J M Nolte

Biohybrid amphiphiles have been prepared from terminal azide functionalised polystyrene and an alkyne functionalised peptide or protein via a Cu(I) catalysed Huisgen [3 + 2] dipolar cycloaddition reaction.

Journal: :Organic materials 2023

Amphiphiles are widely explored for the solubilization of various hydrophobic molecules especially drugs in water. Recently, aromatic amphiphiles emerged as a new class organic semiconductors However, synthesis these systems involves several steps and often requires use expensive metal catalysts. Here we describe design type flexible amphiphilic trication (FAT) its application FAT has been synt...

Journal: :Bioorganic & medicinal chemistry 2009
Richard V Macri Janka Karlovská Gustavo F Doncel Xiaosong Du Bhadreshkumar B Maisuria André A Williams Eko W Sugandhi Joseph O Falkinham Alan R Esker Richard D Gandour

Three series of homologous dendritic amphiphiles--RCONHC(CH(2)CH(2)COOH)(3), 1(n); ROCONHC(CH(2)CH(2)COOH)(3), 2(n); RNHCONHC(CH(2)CH(2)COOH)(3), 3(n), where R = n-C(n)H(2n+1) and n = 13-22 carbon atoms--were assayed for their potential to serve as antimicrobial components in a topical vaginal formulation. Comparing epithelial cytotoxicities to the ability of these homologues to inhibit HIV, Ne...

Journal: :Soft matter 2017
Seng Koon Lim Andrew S W Wong Hans-Peter M de Hoog Padmini Rangamani Atul N Parikh Madhavan Nallani Sara Sandin Bo Liedberg

Many common amphiphiles self-assemble in water to produce heterogeneous populations of discrete and symmetric but polydisperse and multilamellar vesicles isolating the encapsulated aqueous core from the surrounding bulk. But when mixtures of amphiphiles of vastly different elastic properties co-assemble, their non-uniform molecular organization can stabilize lower symmetries and produce novel s...

Journal: :Supramolecular Chemistry 2021

Herein, we present the synthesis of two novel adamantane appended supramolecular self-associating amphiphiles. The antimicrobial efficacy these compounds is determined against both clinically relevant Gram-positive methicillin-resistant Staphylococcus aureus and Gram-negative Escherichia coli. We also explore self-associative properties amphiphiles in polar organic DMSO-d6 0.5% H2O (D2O)/EtOH 1...

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