conclusions the administration of dextrose saline was associated with a shortened active phase and second stage of labor in vaginally delivered nulliparous women. results of 174 objects enrolled, 150 women delivered vaginally and completed the study. there was a significant difference in the duration of active phase between the groups (ns: 270.20 ± 13.37 minutes; d5ns: 206.67 ± 11.72 minutes) (...

In the adult animal, ANG-(1-7) may counterbalance some effects of ANG II. Its effects in the fetus are unknown. Basal ANG-(1-7), ANG I, ANG II, and renin concentrations were measured in plasma from ovine fetuses and their mothers (n = 10) at 111 days of gestation. In the fetus, concentrations of ANG I, ANG-(1-7), and ANG II were 86 +/- 21, 13 +/- 2, and 14 +/- 2 fmol/ml, respectively. In the ew...

BACKGROUND The infusion rate is considered to affect incidence and severity of infusion reactions (IRs) caused by protein formulations. Trastuzumab (TRS) is approved for 90-minute infusion as the initial dose followed by 30-minute infusion with 250 ml saline. In the study, we evaluated the safety of TRS intravenously administered over 30 minutes with 100 ml saline to reduce burden of patients, ...

Amniotic membrane was obtained from 36 mothers seronegative for hepatitis B surface antigen and syphilis, undergoing caesarean section. Membrane was separated from placenta and was washed first with saline and then saline solution containing penicillin. The processed membrane was found to be sterile and useable for up to one week. Of 36 placentas obtained, 33 were utilized in 22 patients, with ...

Amniocentesis and intra-amniotic injection of hypertonic saline to terminate pregnancy in the second trimester has at~ tained great importance in recent [Years. That such a method was not accepted or currently used in leading obstetric institutiolll3 can be easily demonstrated. In Scandinavia, where an average of 3,354 pregnancies were legally terminated annually from 1955 to 1965, abdominal by...

Dilatation and currettage or vaccum aspiration is an accepted method of termination of pregnancy in the fimt trimester. Search is still being made for an ideal method of termination of pregnancy in the 2nd trimester. Between 14-16 weeks of pregnancy vaginal transcervical injection of intra-amniotic saline can be done. After 16 weeks of gestation abdominal or vaginal route can be employed. Vario...

OBJECTIVE To investigate motor evoked potentials during short term L-arginine infusion in cerebral vasospasm after experimental subarachnoid hemorrhage. METHODS Three groups were designated for this study: control group, subarachnoid hemorrhage-saline infusion group, and subarachnoid hemorrhage-L-arginine infusion group. A subarachnoid hemorrhage was created by intracisternal injection of aut...

Acute, high-dose exposure to endotoxin lipopolysaccharide (LPS) in preterm fetal sheep can trigger periventricular white matter lesions (PVL), in association with severe hypotension/hypoxemia and significant mortality. Intriguingly, however, chronic or repeated exposure to LPS can induce tachyphylaxis. We therefore tested the hypothesis that progressive, acute on chronic fetal infection would b...

The purpose of this experimental study was to evaluate the effect of chicken amniotic fluid (AF) on a cross section of rat sciatic nerves. Thirty adult male Sprague-Dawley rats weighing 275 to 300 g, were randomized into three groups treated with (1) amniotic fluid or AF (n=10), (2) normal saline or NS (n=10), and (3) sham surgery (n=10). The AF was aspirated from the amniotic cavity of incubat...

The effect of intraduodenal and intraruminal infusion of short-chain fatty acids (SCFA) on exocrine pancreatic secretions was studied in 27 Polish Merino sheep that were surgically fitted with a common bile duct catheter, a gall-bladder catheter and two duodenal T-cannulas for collection and subsequent return of pancreatic juice, and with a ruminal cannula. Animals were fed ad libitum with sila...