Many bacteria convert bicyclic compounds, such as indole and naphthalene, to oxidized compounds, including hydroxyindoles and naphthols. Pseudomonas aeruginosa, a ubiquitous bacterium that inhabits diverse environments, shows pathogenicity against animals, plants, and other microorganisms, and increasing evidence has shown that several bicyclic compounds alter the virulence-related phenotypes o...

We study the solvent-induced frequency shifts of the OH-stretching mode of 1-naphthol and 2-naphthol in nonpolar/weakly polar solvents, subject to electronic excitation, with ultrafast UV/mid-infrared pump-probe spectroscopy and theoretical modeling based on Pullin's perturbative treatment of vibrational solvatochromic effects. The model is parametrized at the density functional theory (DFT) le...

The oxidative metabolism of benzo(a)pyrene and the conjugative metabolism of 1-naphthol by explant cultures of normal human colon and colonic tumor tissue, obtained at surgery, have been studied. After 24 hr in culture, the explants were exposed to either [1-14C]-1-naphthol (20 to 100 microM) or [3H]-benzo(a) pyrene (1.5 microM) for a further 1.5 to 24 hr. Both normal-appearing tissue and tumor...

Abstract A homochiral metal–organic framework (MOF) comprising [Co(L)(bpe)2(H2O)2]·H2O was prepared using (1R,2R)-(−)-1,2-cyclohexanedicarboxylic acid (H2L) and 1,2-bis(4-pyridyl)-ethylene as organic ligands. The MOF explored chiral stationary phase (CSP) for high-performance liquid chromatography (HPLC) separation of racemates. Nine racemates including naphthol, alcohol, diol, amine, ketone, e...

We demonstrate the photocatalytic protonation of a silylenol ether using 7-bromo-2-naphthol as an ESPT catalyst with phenol as the sacrificial proton source. Greater than 95% conversion is achieved with 1 mol% catalyst. The reaction cycle is dependent on the significantly increased acidity of the catalyst in the excited state as well as the long lifetime for the triplet excited state of 7-bromo...

The new ligand 1-(1,2,4-triazol-4-ylimino-meth-yl)-2-naphthol (L) and the title silver(I) complex, namely bis-[μ-1-(1,2,4-triazol-4-ylimino-meth-yl)-2-naphthol]bis-{[1-(1,2,4-triazol-4-yl-imino-meth-yl)-2-naphthol]silver(I)} dinitrate monohydrate, [Ag(2)(C(13)H(10)N(4)O)(4)](NO(3))(2)·H(2)O, were synthesized. Each silver center in the dimeric complex (related by an inversion centre) is coordina...

1-Naphthol at concentrations ranging from 0.4 to 34.6 mg/l was found in urine collected directly after the end of the work shift from a group of industrial workers employed in distillation of naphthalene oil. The maximum excretion was found one hour after the end of the shift and the mean excretion rate was 0.57 mg/h. Coke plant workers exposed to naphthalene and other aromatic and polycyclic h...

The title compound, C(11)H(9)NO(2), was prepared by a condens-ation reaction of 2-hydr-oxy-1-naphthaldehyde with hydroxyl-ammonium chloride in refluxing ethanol. An intra-molecular O-H⋯N hydrogen bond is observed. In the crystal structure, inter-molecular O-H⋯O and C-H⋯O hydrogen-bond inter-actions result in a two-dimensional network.