In this project, a three-component functionalization of carboxylated shortend multi-walled carbon nanotubes (MWNT-COOH) by Histidine derivative via amidation method have been investigated. The functionalized MWNTs were characterized by Fourier Transform Infrared spectroscopy (FT-IR), Raman spectroscopy, elemental analysis and scanning electron microscopy (SEM). 

Human relaxin-3 is a neuropeptide that is structurally similar to human insulin with two chains (A and B) connected by three disulfide bonds. It is expressed primarily in the brain and has modulatory roles in stress and anxiety, feeding and metabolism, and arousal and behavioural activation. Structure-activity relationship studies have shown that relaxin-3 interacts with its cognate receptor RX...

Abstract Zirconocene triflate is a powerful moisture-tolerant catalyst for activation of C–O bonds in carboxylic acids and alcohols the absence water scavenging techniques. Herein, an overview use this robust metal complex direct amidation, esterification, etherification presented, along with discussion on mechanistic aspects transformations class.

The Bacillus subtilis chemotaxis pathway employs a receptor methylation system that functions differently from the one in the canonical Escherichia coli pathway. Previously, we hypothesized that B. subtilis employs a site-specific methylation system for adaptation where methyl groups are added and removed at different sites. This study investigated how covalent modifications to the adaptation r...

A catalytic protocol for the base-mediated amidation of unactivated esters with amino alcohol derivatives is reported. Investigations into mechanistic aspects of the process indicate that the reaction involves an initial transesterification, followed by an intramolecular rearrangement. The reaction is highly general in nature and can be extended to include the synthesis of oxazolidinone systems...