نتایج جستجو برای: amegakaryocytic thrombocytopenia

تعداد نتایج: 24775  

Journal: :Blood 1961
S L SALTZSTEIN

CCUMULATION of lipid, presumably phospholipid, in histiocytes of the splenic cords has been seen in association with thrombocytopenic purpura in six patients operated on in Barnes Hospital. At the time that each of the first four were examined, a diagnosis or description of lipid histiocytosis of the spleen was made, but after that the constant association with thrombocytopenic purpura was note...

Journal: :Haematologica 2007
Anna Savoia Carlo Dufour Franco Locatelli Patrizia Noris Chiara Ambaglio Vittorio Rosti Marco Zecca Simona Ferrari Filomena di Bari Anna Corcione Mariateresa Di Stazio Marco Seri Carlo L Balduini

BACKGROUND AND OBJECTIVES Congenital amegakaryocytic thrombocytopenia (CAMT) is a rare, autosomal recessive disorder induced by mutations of the gene coding for thrombopoietin (TPO) receptor (c-MPL). Patients initially present with isolated thrombocytopenia that subsequently progresses into pancytopenia. Although the mechanisms leading to aplasia are unknown, the age of onset has been reported ...

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