نتایج جستجو برای: ambrisentan
تعداد نتایج: 197 فیلتر نتایج به سال:
tricle: role of the pericardium and the right ventricle. Circulation 1979;59:32–37. 30. Chang SM, Lin CC, Hsiao SH, Lee CY, Huang WC. Pulmonary hypertension and left heart function: insights from tissue Doppler imaging and myocardial performance index. Echocardiography 2007;24:366–373. 31. YilmazR, Gencer M, Ceylan E, Demirbag R. Impactof chronicobstructivepulmonary disease with pulmonary hyper...
Congenital heart diseases are the most common congenital malformations and account for about eight cases per 1000 births and are often associated with pulmonary arterial hypertension. Increased shear stress and the excess flow through the pulmonary vascular bed due to a systemic-to-pulmonary shunt lead to the development of pulmonary vascular disease and an increase in pulmonary vascular resist...
To elucidate whether the pharmacokinetics (PK) and pharmacodynamics (PD) of sildenafil are influenced differently when it is coadministered with bosentan (S+B) or with ambrisentan (S+A), we evaluated the PK and PD profiles of sildenafil before and after 4-5 weeks of S+A or S+B treatment in patients with pulmonary arterial hypertension. The area under the plasma concentration-time curve of silde...
Objective: The rationale of the current work is to design, develop and optimize mouth dissolving tablet ambrisentan treat hypertension. Methods: Sodium starch glycolate crospovidone were used as super disintegrants in direct compression method create nine mouth-dissolving formulations. Wetting time, drug content, vitro disintegration dispersion dissolution time all assessed for produced Results...
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