background: we compared the wave amplitude of visually evoked potential (vep) between patients with esotropic and anisometropic amblyopic eyes and a normal group. methods: the wave amplitude of vep was documented in 2 groups of persons with amblyopia (15 with esotropia and 28 with anisometropia) and 1 group of individuals with normal visual acuity (n, 15). the amplitude of p100 was recorded mon...

The effects of unilateral lid closure and artificial esotropia on the development of visual acuity were studied in visually immature rhesus monkeys (Macaca mulatta). Irreversible amblyopia occurred in all animals whose lids were sutured between birth and nine weeks of age. Lid closure at the age of 12 weeks did not produce amblyopia. During the age of susceptibility only brief periods of occlus...

Disruption of visual input to one eye during early development leads to marked functional impairments of vision, commonly referred to as amblyopia. A major consequence of amblyopia is the inability to encode binocular disparity information leading to impaired depth perception or stereo acuity. If amblyopia is treated early in life (before 4 years of age), then recovery of normal stereoscopic fu...

Identification of the neural basis of the visual deficits experienced by humans with amblyopia, particularly when associated with strabismus (strabismic amblyopia), has proved to be difficult in part because of the inability to observe directly the neural changes at various levels of the human visual pathway. Much of our knowledge has necessarily been obtained on the basis of sophisticated psyc...

AIMS The study aimed to assess the effect of initial visual acuity and type of amblyopia on the long term results of successfully treated amblyopia. METHODS The visual acuity of 94 patients, who had been successfully treated for unilateral amblyopia by occlusion of the good eye and followed up to the age of 9 years, was examined 6.4 years, on average, after cessation of treatment. Patients we...

Citation: Xi J, Jia W-L, Feng L-X, Lu Z-L, Huang C-B. Perceptual learning improves stereoacuity in amblyopia. Invest Ophthalmol Vis Sci. 2014;55:2384–2391. DOI:10.1167/ iovs.13-12627 PURPOSE. Amblyopia is a developmental disorder that results in both monocular and binocular deficits. Although traditional treatment in clinical practice (i.e., refractive correction, or occlusion by patching and p...

What underlies contrast sensitivity improvements in adults with anisometropic amblyopia following perceptual learning in grating contrast detection? In this paper, we adopted the external noise approach (Z.-L. Lu & B. A. Dosher, 1998) to identify the mechanisms underlying perceptual learning in adults with anisometropic amblyopia. By measuring contrast thresholds in a range of external noise co...

We have compared the effects on visual acuity and binocular functions of grating stimulation (CAM therapy) and full-time occlusion in 38 4-year-old, previously untreated amblyopic children. The patients were divided into subgroups with regard to amblyopia type and fixation pattern. We found that grating stimulation was slightly better than occlusion in improving visual acuity of anisometropic a...

BACKGROUND The excess risk of bilateral visual impairment (BVI; bilateral visual acuity <0.5) among individuals with amblyopia is an argument for screening for amblyopia, but data are scarce. METHODS The risk was estimated by determining the incidence of BVI in the Rotterdam Study, a population-based cohort of subjects aged 55 years or over (n = 5220), including 192 individuals with amblyopia...

purpose: to assess the etiology, demography, surgical management and postoperative complications of ptosis in a referral ophthalmologic center. methods: we reviewed records of 233 ptosis patients managed at labbafinejad hospital during 1998-2003. etiology, age, sex, laterality, family history, amblyopia, past medical history, margin reflex distance and levator function, type of surgery, and pos...