Grain amaranth is a highly nutritious pseudo-cereal with good adaptability to range of environmental conditions and potential be further cultivated in many areas the world. Although crop has adaptability, soil type can influence establishment production; thus, objective this study was evaluate how cultivar, sowing depth, affect emergence early growth grain amaranth. A pot experiment carried out...

Antimicrobial drug development has greatly diminished due to regulatory uncertainty about the magnitude of the antibiotic treatment effect. Herein we evaluate the utility of pharmacometric-based analyses for determining the magnitude of the treatment effect. Frequentist and Bayesian pharmacometric-based logistic regression analyses were conducted by using data from a phase 3 clinical trial of t...

YES-associated protein 2 (YAP2) transcriptional regulator drives a multitude of cellular processes, including the newly discovered Hippo tumor suppressor pathway, by virtue of the ability of its WW domains to bind and recruit PPXY-containing ligands to specific subcellular compartments. Herein, we employ an array of biophysical tools to investigate allosteric communication between the WW tandem...

The new a-pyrone derivative II was isolated in crystalline form from extracts of dormant seeds of Rosa canina. It inhibits germination of seeds of Amaranthus caudatus completely, but reversibly, at conc. > 2.5 x 10~5 m . Its chemical structure was elucidated by mass spectrometry, 'Hand 13CNMR spectroscopy to be 3-methyl-l-oxa-bicyclo (4,1,0) hept-5-en-2-one-4,6-dicarboxylic acid di­ methylester...