Background Alzheimer Management By Albumin Replacement (AMBAR) is a multicenter, randomized, placebo-controlled, Phase IIb/III clinical trial that evaluated the efficacy and safety of Plasma Exchange with replacement (PE-A) in patients mild-to-moderate Alzheimer’s disease (Boada et al., Alzheimers Dement. 2020). PE-A has demonstrated an overall benefit quality life as measured by Quality Life-A...