Aluminum lactate [Al(lact)3] (hydrophilic, hydrolytically unstable) and aluminum acetylacetonate [Al(acae)3] (lipophilic, hydrolytically stable) were tested as potential toxicants to rabbits upon IV administration both as aqueous solutions and as liposome suspensions. Both chemicals behaved as cardiotoxic agents when administered as aqueous solutions, but Al(acae)3 was at least two orders of ma...

A great deal has been learned about the neurotoxicity of aluminum over the past two decades in terms of its ability to disrupt cellular function. Newer evidence suggests that a more central pathophysiological mechanism may be responsible for much of the toxicity of aluminum and aluminofluoride compounds on the brain. This mechanism involves activation of the brain’s innate immune system, primar...

Elemental silicon, present as soluble silicic acid in serum and urine, has been measured by direct current plasma emission spectrometry. The method is precise and accurate, yields a standard curve that is linear up to 1000 mumol/L, and requires only a simple dilution in 10 mL/L HNO3. No spectral or background interferences have been observed from serum or urine; the absolute detection limit for...

The alleviating effect of silicon (Si) supply on aluminum (Al) toxicity was suggested to be based on ex or in planta mechanisms. In our experiments with the Al-sensitive maize (Zea mays) cultivar Lixis, Si treatment but not Si pretreatment ameliorated Al-induced root injury as revealed by less root-growth inhibition and callose formation. Si treatment did not affect monomeric Al concentrations ...

Seedlings of aluminum-tolerant 'Xuegan' (Citrus sinensis) and Al-intolerant 'sour pummelo' (Citrus grandis) were fertigated for 18 weeks with nutrient solution containing 0 and 1.2 mM AlCl₃·6H₂O. Al toxicity-induced inhibition of photosynthesis and the decrease of total soluble protein only occurred in C. grandis leaves, demonstrating that C. sinensis had higher Al tolerance than C. grandis. Us...

Acid-Aluminum (Al) is toxic to plants and greatly affects crop production worldwide. To understand the responses of plants to acid soils and Aluminum toxicity, we examined global gene expression using microarray data in alfalfa seedlings with the treatment of acid-Aluminum. 3,926 genes that were identified significantly up- or downregulated in response to Al3+ ions with pH 4.5 treatment, 66.33%...

The effects of aluminum chloride (AlCl ), ascorbic acid (AA) and/or their combination were 3 investigated on the performance, digestibility, nitrogen balance, caecal microbial activity and biochemical parameters in male New Zealand white rabbits. The experimental rabbits were randomly divided into four groups (n=6/ group). The first group was used as a control, the second group was used to stud...

The common-bean (Phaseolus vulgaris), a widely consumed legume, originated in Mesoamerica and expanded to South America, resulting the development of two geographically distinct gene pools. Poor soil condition, including metal toxicity, are often constraints crop production. Several P. vulgaris miRNAs, miR1511, respond toxicity. MIR1511 sequence from model sequenced genotypes revealed that, as ...

Aluminum phosphide has high toxicity when it is ingested, and in case of contact with moisture, phosphine gas is released. Aluminum phosphide poisoning causes metabolic acidosis, arrhythmia, acute respiratory distress syndrome and shock, and there is no specific antidote. A 17-year-old male patient was referred to our hospital because of aluminum phosphide poisoning with 1500 mg of aluminum pho...