Treatment of alopecia areata remains unsatisfactory. We decided to test if systemic therapy with inosiplex (Isoprinosine(R)), an immunomodulator could influence the disease. Thirty-two subjects with recalcitrant alopecia areata, aged 16-48 years (mean 30.3+/-5.1 years), were randomized into two treatment groups of 16 subjects each. They were assigned to receive either oral inosiplex (group 1), ...

conclusions our study showed that the combined use of elidel and tretinoin was more effective than elidel alone. objectives in this study, we compared the efficacy of topical elidel alone and elidel accompanied with tretinoin in the treatment of alopecia areata. patients and methods this randomized controlled clinical trial was performed on patients with alopecia areata in rasul-e akram hospita...

Protein biochips have a great potential in future parallel processing of complex samples as a research tool and in diagnostics. For the generation of protein biochips, highly automated technologies have been developed for cDNA expression library production, high throughput protein expression, large scale analysis of proteins, and protein microarray generation. Using this technology, we present ...

INTRODUCTION Alopecia areata is an autoimmune inflammatory disease affecting the hair follicles. Researchers are currently interested in whether the presence of bacterial pathogens and/or a history of immunization can trigger an autoimmune response in patients who are genetically predisposed. OBJECTIVES This study aimed to determine whether there is an association between the development of a...

Alopecia areata is a chronic probable auto immune skin disorder characterised by hair loss over the body. Though its psychological status has been debated over the ages presently we have research that points towards a psychosomatic causation of the disorder. The present review paper looks at the psychological factors in alopecia areata, the various studies and prevalence of psychiatric problems...

Thirty cases of alopecia Areata from O.P.D. of Govt. Hospital, Madras were administered Indian Version of schedule of Recent Experience, Taylor's Manifest Anxiety Scale, Beck's Depressive Inventory, Hostility Direction and Hostility Questionnaire of Fould's and Cattell's 16 PF Questionnaire (Form E) to find out antecedent stress, anxiety, depression, hostility and personality factors. Thirty ca...

I have read with interest the brief communication entitled “Treatment of alopecia areata by topical diclofenac sodium gel in comparison to benzoyl peroxide. A novel single blind therapeutic clinical trial” by Sharquie et al.1 The author suggested the use of diclofenac gel as an irritant in alopecia areata, which in other words, by causing inflammation of the affected area but diclofenac has an ...

BACKGROUND Alopecia areata is a recurrent, nonscarring type of hair loss. Different modalities of treatment have been used to induce hair re-growth. AIMS To determine the efficacy of topical garlic gel in the treatment of alopecia areata. METHODS Patients were randomly divided into two groups of garlic gel and placebo. The two groups were advised to follow the treatment twice daily, for thr...