نتایج جستجو برای: allele locus

تعداد نتایج: 205065  

2005
Nejat Mahdieh Elham Tafsiri Morteza Karimipour Mohammad T. Akbari

Genetic markers are used for identity testing and paternity analysis depends on knowing the allele frequencies in the population. Minisatellites show allelic variability in the number of repeat units. We have studied the allele frequencies and heterozygosity of two VNTRs (ApoB and D1S80) in Iranian populations. A total of 96 and 82 chromosomes were analyzed by PCR and gel electrophoresis for Ap...

Journal: :Circulation. Cardiovascular genetics 2012
Gary F Mitchell Germaine C Verwoert Kirill V Tarasov Aaron Isaacs Albert V Smith Yasmin Ernst R Rietzschel Toshiko Tanaka Yongmei Liu Afshin Parsa Samer S Najjar Kevin M O'Shaughnessy Sigurdur Sigurdsson Marc L De Buyzere Martin G Larson Mark P S Sie Jeanette S Andrews Wendy S Post Francesco U S Mattace-Raso Carmel M McEniery Gudny Eiriksdottir Patrick Segers Ramachandran S Vasan Marie Josee E van Rijn Timothy D Howard Patrick F McArdle Abbas Dehghan Elizabeth S Jewell Stephen J Newhouse Sofie Bekaert Naomi M Hamburg Anne B Newman Albert Hofman Angelo Scuteri Dirk De Bacquer Mohammad Arfan Ikram Bruce M Psaty Christian Fuchsberger Matthias Olden Louise V Wain Paul Elliott Nicholas L Smith Janine F Felix Jeanette Erdmann Joseph A Vita Kim Sutton-Tyrrell Eric J G Sijbrands Serena Sanna Lenore J Launer Tim De Meyer Andrew D Johnson Anna F C Schut David M Herrington Fernando Rivadeneira Manuela Uda Ian B Wilkinson Thor Aspelund Thierry C Gillebert Luc Van Bortel Emelia J Benjamin Ben A Oostra Jingzhong Ding Quince Gibson André G Uitterlinden Gonçalo R Abecasis John R Cockcroft Vilmundur Gudnason Guy G De Backer Luigi Ferrucci Tamara B Harris Alan R Shuldiner Cornelia M van Duijn Daniel Levy Edward G Lakatta Jacqueline C M Witteman

BACKGROUND Carotid-femoral pulse wave velocity (CFPWV) is a heritable measure of aortic stiffness that is strongly associated with increased risk for major cardiovascular disease events. METHODS AND RESULTS We conducted a meta-analysis of genome-wide association data in 9 community-based European ancestry cohorts consisting of 20 634 participants. Results were replicated in 2 additional Europ...

Journal: :Genetika 2021

Considering of multiples research genetic in cats, the objective this study was to compare diversity domestic cat population at different spatial and temporal scales. According administrative division city Cali, 8 colonies (localities) were chosen, which together form 5 subpopulations within for sampling. The phenotype from each individual?s coat recognized subsequent calculation allele frequen...

Journal: :Evolutionary computation 2003
Robert B. Heckendorn Alden H. Wright

This paper addresses the problem of discovering the structure of a fitness function from binary strings to the reals under the assumption of bounded epistasis. Two loci (string positions) are epistatically linked if the effect of changing the allele (value) at one locus depends on the allele at the other locus. Similarly, a group of loci are epistatically linked if the effect of changing the al...

2011
Venusia Cortellini Nicoletta Cerri Andrea Verzeletti

AIM To investigate allele distribution and genetic parameters of a population-based sample from Maghreb region. METHODS Allele frequencies for 5 new autosomal short tandem repeat (STR) markers (D10S1248, D22S1045, D2S441, D1S1656, and D12S391) and several forensic parameters were determined for 95 unrelated individuals. RESULTS The combined power of discrimination and power of exclusion for...

Journal: :Journal of animal science 1998
E Casas J W Keele S D Shackelford M Koohmaraie T S Sonstegard T P Smith S M Kappes R T Stone

A locus near the centromere of bovine chromosome 2 is responsible for muscle hypertrophy (mh) in cattle. The objectives of this study were to refine the genomic region in which the locus resides and to assess the effects of a single copy of the mh allele on carcass and birth traits. Two half-sib families were developed using a Belgian Blue x MARC III (n = 246) or a Piedmontese x Angus (n = 209)...

Journal: :Genetics 2012
Sabin Lessard Amir R Kermany

We use the ancestral influence graph (AIG) for a two-locus, two-allele selection model in the limit of a large population size to obtain an analytic approximation for the probability of ultimate fixation of a single mutant allele A. We assume that this new mutant is introduced at a given locus into a finite population in which a previous mutant allele B is already segregating with a wild type a...

2017
Abdelhakim Ferradji Yasmin D'Souza Chee Loong Saw Karim Oualkacha Lucie Richard Ruth Sapir-Pichhadze

INTRODUCTION Donor-recipient HLA compatibility is an important determinant of transplant outcomes. Allele-group to allele-level imputations help assign HLA genotypes when allele-level genotypes are not available during donor selection. METHODS We evaluated the performance of HaploStats, an allele-level multi-locus HLA genotype imputation tool from the National Marrow Donor Program, in a cross...

2017
Gilberto Bento Jarkko Routtu Peter D Fields Yann Bourgeois Louis Du Pasquier Dieter Ebert

Negative frequency-dependent selection (NFDS) is an evolutionary mechanism suggested to govern host-parasite coevolution and the maintenance of genetic diversity at host resistance loci, such as the vertebrate MHC and R-genes in plants. Matching-allele interactions of hosts and parasites that prevent the emergence of host and parasite genotypes that are universally resistant and infective are a...

Journal: :Journal of Zoology 2021

The black sparrowhawk (Accipiter melanoleucus) is a color-polymorphic sub-Saharan raptor, with adults occurring in two discrete color morphs: dark and light. It has previously been suggested that plumage coloration determined by one-locus two-allele system, the light allele being dominant over allele. Here, we revisit assumption an extended dataset of 130 individuals pedigree information from 7...

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