The novel quinoline alkaloid scolopendrine was isolated from the centipede, Scolopendra subspinipes mutilans L. Koch. The structure was determined to be 2-hydroxy-7-[(4-hydroxy-3-methoxyphenyl)methyl]-3-methoxy-8-quinolyl sulfate on the basis of high-resolution electron-spray ionization mass spectroscopy and two-dimensional NMR spectral data. Unlike quinoline alkaloids so far reported, scolopen...

Narcissus spp. are of great importance to pharmaceutical industries because of biosynthesis of Amaryllidaceae alkaloids. N. tazetta with several varieties is a widespread species, native to the Mediterranean region with considerable distribution in Iran. In the present study, calli, roots and bulblets were regenerated from N. tazetta var. Meskin. In order to report alkaloid profile and quantify...

Article history: Received on: 20/01/2015 Revised on: 18/02/2015 Accepted on: 21/03/2015 Available online: 15/05/2015 Annona squamosa and its active alkaloid content (-) Anonaine are known for antiepileptic activity on the basis of literature review. The objective of this study was to establish neuroprotection by Annona squamosa and its active alkaloid content (-) Anonaine as an antiepileptic ag...

BACKGROUND Methanol extracts and alkaloid fractions of different parts of four plant species belonging to Solanaceae family and used in Mexican traditional medicine were investigated for their total phenolic contents, anti-inflammatory and antioxidant properties. MATERIALS AND METHODS The total phenolic compounds of each extract was determined according to the Folin-Ciocalteu method, while th...

Anti typhoid properties of methanol leaves extract of Acacia nilotica was investigated. The phytochemical screenings for detection of the presence of bioactive constituents were carried out. A of mice with Salmonella typhi parasites treating them with leave extract of Acacia nilotica followed by widal tests. The phytochemical screening of the methanol leave extract of Acacia nilotica revealed t...

INTRODUCTION The Chinese extract Rhizoma coptidis is well known for its anti-inflammatory, antioxidative, antiviral, and antimicrobial activity. The exact mechanisms of action are not fully understood. METHODS We examined the effect of the extract and its main compound, berberine, on LPS-induced inflammatory activity in a murine macrophage cell line. RAW 264.7 cells were stimulated with LPS a...

The aim of this study is to evaluate anti-inflammatory activity and to determine phytochemical constituent of ethanolic leaf extract of Aegle marmelos(L.) Corr. Serr.. Plant materials are collected from Punjab. Ethanolic extract was screened for different phytochemical constituents. Acute toxicity studies are done according to OECD guidelines. Ethanolic extracts were screened for anti-inflammat...