We study the interaction of berberine and sanguinarine (plant alkaloids) with DNA in aqueous solutions, by using optical spectroscopy methods (absorption and fluorescence). The dependencies of alkaloid spectral characteristics on the concentration ratio N/c between the DNA base pairs and alkaloid molecules in the solutions are considered, and the manifestations of the alkaloid– DNA binding are ...

background: plants and fruits are an essential component of the universe. human beings have used those as medicine from the very beginning of time. according to holy quran, the fruits like grape, date, fig, olive and pomegranate are gifts and heavenly fruits of god. eighteen fruits and plants name have been mentioned in the holy book of moslem. a phytochemical screening of these fruits and plan...

a new alkaloid (1) and two known compounds (2 and 3) were isolated from the blue-greenalga arthrospira platensis. their structures were determined on the basis of spectroscopic data.according to the obtained data and values in the literature, the compounds were concluded to beeckol.

ergovaline, the main ergopeptine alkaloid produced in tall fescue ( fescue arundinacea schreb.) infected with endophyte ( neotyphodium coenophialum morgan- jones & gams), is known to cause tall fescue toxicosis. this study was conducted to examine the presence of fungal endophytes in five populations of tall fescue collected from various regions of iran. the existence of neotyphodium mycelia in...

A fast, practical ambient extraction methodology followed by isocratic liquid chromatography (LC) analysis with UV detection was validated for the determination of berberine, hydrastine, and canadine in goldenseal (Hydrastis canadensis L.) root powder. The method was also validated for palmatine, a major alkaloid present in the possible bioadulterants Coptis, Oregon grape root, and barberry bar...

The opium poppy, Papaver somniferum, is one of mankind's oldest medicinal plants. Opium poppy today is the commercial source of the narcotic analgesics morphine and codeine. Along with these two morphinans, opium poppy produces approximately eighty alkaloids belonging to various tetrahydrobenzylisoquinoline-derived classes. It has been known for over a century that morphinan alkaloids accumulat...

Testing of lupine varieties for alkaloids was performed in the period 2006-2010 at the Voke Branch of the Lithuanian Institute of Agriculture in the course of a competitive trial of feeding lupine (Lupinus sp.). Samples of feeding yellow lupine (Lupinus luteus L.) varieties as well as narrow-leaved lupine (Lupinus angustifolius L.) were used. The alkaloid concentration was assessed in the perio...

Varieties of alkaloids are known to be produced by various organisms, including bacteria, fungi and plants, as secondary metabolites that exhibit useful bioactivities. However, understanding of how those metabolites are biosynthesized still remains limited, because most of these compounds are isolated from plants and at a trace level of production. In this review, we focus on recent efforts in ...