نتایج جستجو برای: alginate nanoparticles
تعداد نتایج: 115076 فیلتر نتایج به سال:
meso-Tetra(N-methyl-4-pyridyl) porphine tetra tosylate (TMP) is a photosensitizer that can be used in photodynamic therapy (PDT) to induce cell death through generation of reactive oxygen species in targeted tumor cells. However, TMP is highly hydrophilic, and therefore, its ability to accumulate intracellularly is limited. In this study, a strategy to improve TMP uptake into cells has been inv...
The present work aimed at studying the interaction between insulin and SiNP surfaced with mucoadhesive polymers (chitosan, sodium alginate or polyethylene glycol) and the evaluation of their biocompatibility with HepG2 and Caco-2 cell lines, which mimic in vivo the target of insulin-loaded nanoparticles upon oral administration. Thus, a systematic physicochemical study of the surface-modified i...
Introduction Ca plays a vital role in many biological processes including cell differentiation and apoptosis, cardiac contractility, neurotransmission and brain function. 1 Because of the importance of Ca levels in maintaining proper function and in diseases, there is an increasing need for the development of new robust imaging platforms to perform in vivo detection of changes in Ca levels in w...
Alginate-dextran sulfate-based particles obtained by emulsification/internal gelation technology can be considered suitable carriers for oral insulin delivery. A rational study focused on the emulsification and particle recovery steps was developed in order to reduce particles to the nanosize range while keeping insulin bioactivity. There was a decrease in size when ultrasonication was used dur...
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