Stress is part of everyone's life which may be severe in geriatric population due to multiple and interrelated factors. A cross sectional study was carried out among hundred geriatric people living in an urban area of Dharan with an aim of identifying the level of stress in this population and to find out its association with different demographic variables. Convenient sampling technique was us...

Here we describe a prediction-based framework to analyze omic data and generate models for both disease diagnosis and identification of cellular pathways which are significant in complex diseases. Our framework differs from previous analysis in its use of underlying biology (cellular pathways/gene-sets) to produce predictive feature-disease models. In our study of alcoholism, lung cancer, and s...

Drunkenness and/or hypoglycaemia are possible causes of unusual behavior in a person with diabetes. The aim of this study was to demonstrate different methods which were used in two contradictory reviews of experts for retrospective assessment of a patient's condition in the course of a car crash: An insulin-treated driver caused a car accident resulting in injuries to two men. He was accused o...

American Indian/Alaska Natives have high rates of alcohol-related arrests and are overrepresented in justice systems. To understand the relationship between alcohol dependence, treatment, and alcohol-related incarceration, this study queried American Indian/Alaska Natives currently in remission from alcohol dependence. Participants reported receiving 0 to 43 treatment experiences. Moreover, par...

The relation between serum osmolality and blood-alcohol was studied prospectively in 565 acute trauma patients. The two measurements were closely correlated. It is therefore possible to estimate the blood-alcohol from serum osmolality to assist in the clinical management of acutely injured patients.

Robert Garrett emigrated from Scotland to Van Diemen's Land (now Tasmania) in 1822. Within a few months of arrival he was posted to the barbaric penal colony in Macquarie Harbour, known as Sarah Island. His descent into alcoholism, medical misadventure and premature death were related to his largely unsupported professional environment and were, in many respects, typical of those subjected to t...