Background/aims Non-alcoholic fatty liver disease is one of the most common chronic liver diseases. Some risk factors are known to influence the development of non-alcoholic fatty liver disease, but the effect of tobacco smoking on the progression of non-alcoholic fatty liver disease is controversial. The main goal of this systematic review and meta-analysis is to investigate the association be...

INTRODUCTION AND AIMS Toll-like receptor 4 and proinflammatory cytokines play a central role in the progression of nonalcoholic fatty liver disease. We investigated IL-1, IL-6 and TNFα production and toll-like receptor 4 in both--obese and lean patients with non-alcoholic fatty liver disease who met different sets of metabolic syndrome criteria and linked the results with the disease burden. ...

Non-alcoholic fatty liver disease is a serious health problem linked to obesity and type 2 diabetes. To investigate the biological outcome and therapeutic potential of hepatic fatty acid uptake inhibition, we utilized an adeno-associated virus-mediated RNA interference technique to knock down the expression of hepatic fatty acid transport protein 5 in vivo prior to or after establishing non-alc...

objective: nonalcoholic fatty liver disease (nafld) is the most common form of liver disease in the world and it is one of the liver transplantation causes. the present study aimed to investigate the effect of purslane seeds on anthropometric parameters, fasting blood glucose (fbs), and liver enzymes in patients with nonalcoholic fatty livers. materials and methods: in this clinical trial, 54 p...

background: omega-3 fatty acids have established beneficial effects for cardiovascular disease. the use of omega-3 supplements for patients with non-alcoholic fatty liver disease (nafld) was proposed. the purpose of this study was to review the relationship between omega-3 fatty acids intake and nafld. methods: in this study, the terms such as nafld, omega-3 fatty acids, docosahexanoic acid, an...

Comparison of the Therapeutic Effects Melatonin, Metformin and Vitamin E on Non-Alcoholic Fatty Liver Disease: A Randomized Clinical Trial

BACKGROUND Although it is known that losing weight has an effect on the treatment of non-alcoholic fatty liver disease, the studies that show how losing weight affects the non-alcoholic fatty liver disease for the normal weight male adults are limited so far. In this study, we set body mass index as criteria and investigated how the weight changes for 4 years makes an impact on the risk of non-...

background: some evidence, not in large study populations, suggests that nonalcoholic fatty liver disease (nafld) and metabolic syndrome (mets) share common interactions. we aimed to determine the prevalence of nafld and mets in a large population registered to kavar cohort study center. we also assessed the role of each component of mets in nafld existence. methods: data were obtained from 341...

background non-alcoholic fatty liver disease (nafld) is a common liver disease in the western population and expanding disease in the world. pathological changes in fatty liver are like alcohol liver damage, which can lead to end-stage liver disease. the prevalence of nafld in obese or overweight people is higher than general population, and it seems that people with high body mass index (bmi) ...