INTRODUCTION HISTORICAL personages are often alleged to have suffered from certain diseases or disabilities. Sometimes there is good evidence for this, but sometimes when the evidence is examined one wonders how the belief originated. At least three historical characters, and one biblical one, are frequently referred to as albinos. Two of them, Edward the Confessor and Timur, were real people, ...

Les auteurs rapportent un cas d'un carcinome basocellulaire non décris dans la littérature de notre pays chez un adulte jeune congolais âgé de 25 ans, de sexe masculin présentant une récidive probable de la tumeur. Cette observation permet de décrire le carcinome basocellulaire chez un sujet noir albinos, et de souligner les particularités thérapeutiques. Pan African Medical Journal. 2015; 20:2...

Skin color is determined by epidermal melanin content, the function of which remains poorly understood. Clinically, there is a lower incidence of melanoma in individuals with high levels of constitutive brown/black pigment and/or acquired pigmentation (i.e. tanning). Conversely, individuals with red hair, blue eyes, and inability to tan are at higher risk for developing melanoma. Therefore, pig...

Aim: The purpose of this study was to investigate the effects cigarette smoke. Duration & Place Study: Jan 2018 may 2021 Rashid Latif medical college Lahore Material and Method: Two different groups male albino rats were exposed smoke using a specially developed smoking machine for duration three months on daily basis over course experiment. Both populations made up entirely albinos. Result...

Flash visual evoked potentials (F. VEPs) and electroretinograms (ERGs) were recorded in a total of 20 young children with albinism (age range 5 months to 11 years, mean 4 years). All recordings were made without sedation. There were 13 oculocutaneous cases (one with Hermansky-Pudlak syndrome) and seven ocular albinos. Monocular flash stimulation commonly elicited an asymmetrical occipital VEP d...

Two congenic strains of RCS rats, RCS-p/+ and RCS-c, have been developed that differ from the parental strain at genetic loci affecting pigmentation. Inbred RCS rats are pink-eyed, while RCS-p/+ rats produce segregating litters of pink-eyed (p/p) and black-eyed (p/+) offspring, and RCS-c rats are albinos. All the strains are homozygous for the mutant form of the retinal dystrophy gene. The blac...

Melanin provides a crucial filter for solar UV radiation and its genetically determined variation influences both skin pigmentation and risk of cancer. Genetic evidence suggests that the acquisition of a highly stable melanocortin 1 receptor allele promoting black pigmentation arose around the time of savannah colonization by hominins at some 1-2 Ma. The adaptive significance of dark skin is ge...