Objective: This study was undertaken to evaluate the effect of vestibular stimulation on motor coordination in Parkinson’s disease (PD) induced mice. Methods: 18 healthy adult male Swiss albino mice were used this study. Vestibule stimulated by caloric (CVS). Pesticide Rotenone induce (PD). Motor assessed fall-off time and activity score using rotarod actophotometer, respectively. Results: In t...

Due to the ozone layer depletion an increased global warming observed, which allows UVB radiation penetrate atmosphere and have deadly effects on people. It is thought that short- long-term are exposed daily has biological organisms humans. Concerning effect of radiations, we examine automatic mechanism by a specific amount induces oxidative stress hyperthyroidism. For these examinations 12 adu...

The aim of the present study was to evaluate Vitamin C (VC) as a potent natural antioxidant to mitigate the genotoxic effects of Arsenic trioxide and sodium fluoride in Swiss albino mice in vivo. The study was divided into eight groups consisting of control treated with normal saline (Group I), Group II, III, IV, V, VI, VII and the VC group with only Vitamin C (500 mg/kgbw). Arsenic trioxide (4...

Background: This study was carried out to observe the radioprotective effects of Rosemarinus officinalis leaves extract (ROE) against radiation-induced histopathological alterations in liver of mice. Materials and Methods: Adult Swiss albino mice were exposed to 6 Gy gamma radiation in the presence (experimental) or absence (control) of ROE to study the qualitative and quantitative alt...

Albinism is due to a lack of pigmentation in hair, skin and eye, and has been shown to occur in several animal species. Mutations of the tyrosinase (TYR) gene account for albinism in domestic cats, rabbits, cattle, mice and rats. In this study, we demonstrate that a TYR mutation accounts for albinism in the ferret (Mustela putorius furo). The coding sequence of the five exons of TYR was determi...

The Annona muricata (Family-Annonaceae) fruit contain annonaceous acetogenins which have an effect on cancer cell as reported in many research studies. This study was aimed to evaluate the of methanolic extract (MFEAM) breast histology and invasive MNU-induced mice. Fifty female albino mice were divided into five groups (of ten each): control; cancer; + 200 mg/kg, 300 mg/kg 500 mg/kg. indicates...

METHODS Histological studies were performed on mito chondria in the livers of mice bearing malignant tumors. A total of 30 mice was used in the experi ment. The tumors were : transplanted fibrosar coma of the albino mouse, 9 animals ; Meyer tumor of the albino mouse (a mammary tumor of Brazil ian origin), 5 animals; spontaneous and trans planted mammary carcinoma of the CSH strain mouse, S anim...

background: radiotherapy is the main modality of cancer treatment. there are many chemical radioprotectors which unfortunately have lethal or toxic effect. therefore the search is on to find out natural plant based radioprotectors. a well known medicinal plant,which is more acceptable to the body, tinospora cordifolia, was tested in animal tissues against gamma radiations. radioprotective effec...

The aim of the present study was to evaluate Vitamin C (VC) as a potent natural antioxidant to mitigate the genotoxic effects of Arsenic trioxide and sodium fluoride in Swiss albino mice in vivo. The study was divided into eight groups consisting of control treated with normal saline (Group I), Group II, III, IV, V, VI, VII and the VC group with only Vitamin C (500 mg/kgbw). Arsenic trioxide (4...

PURPOSE To explore the effects of light exposure and deprivation on the distribution and function of microglia in the subretinal space of mice. METHODS Using a monoclonal antibody, 5D4, that identifies resting, ramified microglia, the distribution and density of microglia in the retina, and the subretinal space were determined by confocal microscopy and by immunohistochemistry of cryopreserve...