OBJECTIVE: To investigate the serum antioxidant capacity and status of liver function parameters in Hepatitis B virus (HBV) C Virus (HCV) infected patients. METHODS: In this case-control study, fifty patients with HBV (28 male & 22 females), HCV females) age gender matched healthy controls were enrolled from May to August 2016. The was determined by measuring trolox equivalent oxidant (TEAC...

The aim of this research was to evaluate the role zinc supplementation on reduction heat stress in local lambs during hot season. In current experiment, twenty-seven were housed indoor individual pens (1.50 × 1.30m). Zinc added fresh drinking water three different levels namely T1 (0 mg Zn/day), T2 (36 Zn/day) and T3 (72 Zn/day). Serum (zinc; µmol/L), Alkaline phosphate (ALP; U/I), Alanine amin...

OBJECTIVES Biochemical abnormalities after living-donor hepatectomy are attributed to the loss of liver volume and steatosis or fibrosis. In this study, we evaluated the intraoperative biochemical changes caused by the separation of the hepatic lobes before removal and the impact of those changes on postoperative biochemical abnormalities in patients who underwent adult-to-adult living-donor li...

OBJECTIVE The present pilot trial was carried out to evaluate the effects of an acute treatment with a mixture containing 500 million of Lactobacillus bulgaricus and Streptococcus thermophilus per day in patients with non alcoholic fatty liver disease (NAFLD). RESEARCH METHODS A sample of 30 patients with NAFLD (diagnosed by liver biopsy) was enrolled and 28 patients were analyzed in a double...

The chemopreventive effects of kolaviron, a natural antioxidant bioflavonoid from the seeds of Garcinia kola, on aflatoxin B1 (AFB1)-induced genotoxicity and hepatic oxidative damage was investigated in rats. Kolaviron administered orally at a dose of 200 mg/kg once a day for the first 2 weeks and then 100 mg/kg twice a day for the last 4 weeks of AFB1 (2 mg/kg, single dose, intraperitoneal) tr...

Heart tissue injury may release cardiac enzymes into the circulation and elevate serum enzyme levels (LaDue, Wroblewski, and Karmen, 1954). Many enzymes become raised, but three enzymesaspartate aminotransferase (EC 2.6.1.1), creatine kinase (EC 2.7.3.2), and lactate dehydrogenase (EC 1.1.1.27)-have proved of particular diagnostic value. In addition, determination of lactate dehydrogenase isoen...

This study was designed to evaluate the effects of Jatropha gossypifolia flower extract on some selected biochemical indices in albino rats. Experimental design involves twenty (20) rats which were divided into four groups five animals each. Group I received distilled water (vehicle), group II, III and IV (50, 100 200mg/kg bwt) respectively for a period 14-day. The anaesthetized 24hrs after las...

BACKGROUND Petroselinum crispum, a bright green biennial shrub is widely used traditionally as a food additive and herbal remedies for many ailments. This study therefore aimed to assess the toxic effects of its leaf extract using some biochemical, haematological parameters. METHODS The toxic effects were assessed by quantifying liver enzymes such as serum aspartate amino transferase (AST), a...

Arsenic and hexavalent chromium toxicity results from their ability to interact with sulfahydryl groups of proteins and enzymes, and to substitute phosphorus in a variety of biochemical reactions. Alanine aminotransferase (ALT; E.C: 2.6.1.2) and Aspartate amino transferase (AST; EC 2.6.1.1) play a crucial role in transamination reactions and can be used as potential biomarkers to indicate hepat...

BACKGROUND In Human Immunodeficiency Virus (HIV) infected patients on antiretroviral treatment (ART), hepatotoxicity is life threatening. Its outcome may lead to liver failure and death. This study was conducted to determine the rate and determinants of elevated alanine amino transferase (ALT) (referred as >40IU/L for both males and females). METHODS A cross sectional study was conducted on H...