BACKGROUND Oral leukoplakia (OL) is a common oral precancerous lesion. Cotton-swab cryotherapy (CSC) is commonly used for treating skin lesions but is rarely used for treating OL lesions. METHODS Sixty OL lesions were treated by CSC once every 2 weeks until complete regression (CR) of the lesion had been achieved. RESULTS CR was achieved in all 60 OL lesions after an average of 6.3 treatmen...

A polar fraction obtained from banana fruit pulp by high-vacuum distillation / solvent extraction (pentane-dichloromethane, 2 + 1) and subsequent liquid chromatography on silica gel was derivatized with isopropylisocyanate. Separation of enantiomers of heptan-2-ol and Z-4-hepten-2-ol was performed via their carbamates by means of multidimensional gas chromatography using an achiral (D B -5, col...

Streptomyces spp. have the ability to produce a wide variety of secondary metabolites that interact with the environment. This study aimed to discover antifungal volatiles from the genus Streptomyces and to determine the mechanisms of inhibition. Volatiles identified from Streptomyces spp. included three major terpenes, geosmin, caryolan-1-ol and an unknown sesquiterpene. antiSMASH and KEGG pre...

Inhibition of nitric oxide synthase (NOS) activity in vivo impedes hypertrophy in the overloaded rat plantaris. We investigated the mechanism for this effect by examining early events leading to muscle growth following 5 or 12 days of functional overload. Male Sprague-Dawley rats (approximately 350 g) were randomly divided into three treatment groups: control, N(G)-nitro-L-arginine methyl ester...

Branched five carbon (C5) alcohols are attractive targets for microbial production due to their desirable fuel properties and importance as platform chemicals. In this study, we engineered a heterologous isoprenoid pathway in E. coli for the high-yield production of 3-methyl-3-buten-1-ol, 3-methyl-2-buten-1-ol, and 3-methyl-1-butanol, three C5 alcohols that serve as potential biofuels. We first...

Joint pain is one of the most common complaints with many possible causes.Some medicines used for joint pain relief such as NSAIDs have substantial and frequent side effects. Topical route possibly reduces adverse reactions by maximizing local delivery and minimizing systemic toxicity. Throughout history, plants have been the most important sources of medicines for human health and Iranian Trad...

Ontology Learning (OL) is the computational task of generating a knowledge base in the form of an ontology given an unstructured corpus whose content is in natural language (NL). Several works can be found in this area most of which are limited to statistical and lexico-syntactic pattern matching based techniques (Light-Weight OL). These techniques do not lead to very accurate learning mostly b...

Giger, Julia M., Fadia Haddad, Anqi X. Qin, and Kenneth M. Baldwin. Functional overload increases -MHC promoter activity in rodent fast muscle via the proximal MCAT ( e3) site. Am J Physiol Cell Physiol 282: C518–C527, 2002. First published October 24, 2001; 10.1152/ ajpcell.00444.2001.—Functional overload (OL) of the rat plantaris muscle by the removal of synergistic muscles induces a shift in...

joint pain is one of the most common complaints with many possible causes.some medicines used for joint pain relief such as nsaids have substantial and frequent side effects. topical route possibly reduces adverse reactions by maximizing local delivery and minimizing systemic toxicity. throughout history, plants have been the most important sources of medicines for human health and iranian trad...

Abstract By monitoring biomarkers in urine, personal exposure to selected chemical substances can be assessed. In this paper, we describe the of 7 benzophenone and 2 camphor UV-filters 11 metabolites polycyclic aromatic hydrocarbons (OH-PAHs) 454 urine samples collected from mothers new-borns an industrial (Karvina) reference area (Ceske Budejovice) over winter summer seasons. The analytical me...