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OBJECTIVE To assess the relationship between stages of age-related maculopathy (ARM) and cardiovascular disease and cardiovascular disease risk factors, including serum lipid and plasma fibrinogen levels, smoking, cardiovascular events, systemic hypertension, diabetes mellitus, and obesity. DESIGN A cross-sectional study of 3654 subjects from a defined geographic area identified subjects with...

Age-related macular degeneration (ARMD) is a severe disease affecting visual function in the elderly. Currently available surgical and medical options do not guarantee a significant impact on the outcome of the disease. We describe the effects of nerve growth factor eye drop treatment in a 94 years old female with ARMD, whose visual acuity was progressively worsening in spite of previous surgic...

Background and Aims: Age-related macular degeneration (ARMD) is a degenerative retinal disorder that causes progressive loss of central vision in older adults. The study aimed to determine the effect of asymmetric dimethylarginine (ADMA) as oxidizing metabolite and paraoxonase (PON1) activity within its phenotypes as an antioxidant agent in the development of such multifactorial disease. Mater...

Suprachoroidal hemorrhage is a rare but dreadful event. We report the case of an 86-year-old man with age-related macular degeneration (ARMD) in both eyes. He had been receiving anticoagulation therapy for several years for systemic disease. He presented with severe headache and intractable pain in his right eye. Vision was no light perception, and the intraocular pressure was 50 mmHg in the ri...

OBJECTIVE To assess the association of visual impairment, age-related macular degeneration (ARMD), and cataract with long-term mortality. METHODS At baseline, 3654 persons 49 years and older were examined in the Blue Mountains Eye Study (1992-1994). Standardized photographic grading was used to assess ARMD and cataract. Mortality and causes of death occurring between baseline and December 31,...