Background: Alkaloids are a group of nitrogen- containing natural compounds derived from a variety of sources including bacteria, fungi, marine organisms and plants. Materials and methods: Fruits, stem or leaves were collected from the Zagros highlands around Azna or Khoramabad city, dried and powdered before being extracted in a soxhalet apparatus. The extract was filtered and concentrated u...

The antibacterial activity of a series of ionic liquids containing short-chained 1-alkyl-3-methylimidazolium cations ([Cnmim+]; n = 2, 4, 6 and 8) and bis (trifluoromethylsulfonyl) imide anion ([Tf2N]) against E. coli and B. subtilis was measured, for the first time. All ILs used in this work were synthesized and analyzed by Fourier transform i...

Introduction: Thymbra spicata (T. spicata) is a conventional medicinal herb which is commonly used in the folklore medicine system of Iran. Aim of the study was to assess the antibacterial activity of the essential oil and hudroalcholic extract of the plant T. spicata on some important bacteria. Materials & methods: The essential oil and extract of T. spicata were obtained by hydrodistillation ...

non-steroidal anti-inflammatory drugs (nsaids) have shown antibacterial activity in some recent studies. the aim of this study was to evaluate the antibacterial effect of diclofenac against enterococcus faecalis (e. faecalis) as a resistant endodontic bacterium in comparison with ibuprofen, calcium hydroxide and amoxicillin.the antibacterial activity of materials was evaluated using agar diffus...

A new group of 4-(Imidazolylmethyl) quinoline derivatives possessing a methylsulfonyl COX-2 pharmacophore at the para position of the C-2 phenyl ring were designed and synthesized as selective COX-2 inhibitors and in-vitro anti breast cancer agents. In-vitro COX-1 and COX-2 inhibition studies showed that all the compounds were potent and selective inhibitors of the COX-2 isozyme with IC50 value...

Pseudomonas aeruginosa is an important opportunistic pathogen causing widespread infections by numerous virulence factors. Increasing resistance to antibiotics makes the Pseudomonas infections treatment further difficult. The purpose of this study was to evaluate antimicrobial characteristics of essential oils from Matricaria chamomilla, Artemisia persica, Zataria multiflora, Myrtus communis, R...

Plants used for traditional medicine contain a wide range of substances which can be used to treat various infectious diseases. Hence, antibacterial activities of ethanolic extracts of 19 plant species were studied against multi-drug resistant clinical isolates using agar well diffusion method. Extracts of Liquidambar orientalis, Vitis vinifera,?? ?????????????????????? ????????????????????,...

Pseudomonas aeruginosa is an important opportunistic pathogen causing widespread infections by numerous virulence factors. Increasing resistance to antibiotics makes the Pseudomonas infections treatment further difficult. The purpose of this study was to evaluate antimicrobial characteristics of essential oils from Matricaria chamomilla, Artemisia persica, Zataria multiflora, Myrtus communis, R...

Euphorbiaceae is a family of plant spread in all parts of the world except very cold regions. The genus Euphorbia consists of over eighty-two species grown wildly in Iran. Some of Euphorbia species are used in the treatment cancer and tumors in different countries. The genus Euphorbia has been the source of a large number of biological active compounds. In this study petroleum ether, ether, eth...