نتایج جستجو برای: advanced glycation end productsages

تعداد نتایج: 634407  

Journal: :The FEBS journal 2006
Ricardo A Gomes Hugo Vicente Miranda Marta Sousa Silva Gonçalo Graça Ana V Coelho António E Ferreira Carlos Cordeiro Ana Ponces Freire

Protein glycation by methylglyoxal is a nonenzymatic post-translational modification whereby arginine and lysine side chains form a chemically heterogeneous group of advanced glycation end-products. Methylglyoxal-derived advanced glycation end-products are involved in pathologies such as diabetes and neurodegenerative diseases of the amyloid type. As methylglyoxal is produced nonenzymatically f...

Journal: :The Biochemical journal 2008
Ricardo A Gomes Luís M A Oliveira Mariana Silva Carla Ascenso Alexandre Quintas Gonçalo Costa Ana V Coelho Marta Sousa Silva António E N Ferreira Ana Ponces Freire Carlos Cordeiro

Protein glycation is involved in structure and stability changes that impair protein functionality, which is associated with several human diseases, such as diabetes and amyloidotic neuropathies (Alzheimer's disease, Parkinson's disease and Andrade's syndrome). To understand the relationship of protein glycation with protein dysfunction, unfolding and beta-fibre formation, numerous studies have...

Journal: :iranian journal of medical sciences 0
parisa younessi centre for complementary medicine research, university of western syd-ney, campbelltown campus, sydney, australia; faculty of applied science, university of canberra, canberra, australia ali yoonessi department of neuroscience, school of advanced medical technologies, tehran university of medical science, tehran, iran; iranian national center for addiction studies, tehran university of medical sciences, tehran, iran

glycation is a protein modification, which results in a change in a protein structure. glycation is believed to be the etiology of various age-related diseases such as diabetes mellitus and alz-heimer’s disease (ad). activation of microglia and resident macrophages in the brain by glycated proteins with subsequent oxidative stress and cytokine release may be an important factor in the progressi...

Journal: :Food Biotechnology 2021

Advanced glycation end products (AGEs) are toxic with a high capacity to cause damages health, mainly associated diabetes complications. In this study, soybean isoflavone extracts were subj...

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