OBJECTIVE To determine whether a baseline (random) cortisol concentration <25 microg/dL in patients with septic shock was a better discriminator of adrenal insufficiency than the standard (250 microg) and the low-dose (1 microg) corticotropin stimulation tests as assessed by the hemodynamic response to steroid replacement. SETTING Intensive care unit. PATIENTS Fifty-nine patients with septi...

In a double-blind study 10 patients with chronic asthma received beclomethasone dipropionate 400 mug daily in a Freon propellant from a pressurized dispenser, and 10 patients received the Freon propellant alone. At the start of the trial each patient was receiving long-term maintenance treatment with oral prednisolone in a dose of 7.5 to 15 mg daily. The daily dose of prednisolone was reduced b...

UNLABELLED A functional lesion in corticotrophin (ACTH)-independent Cushing's syndrome is difficult to distinguish from lesions of bilateral adrenal masses. Methods for distinguishing these lesions include adrenal venous sampling and (131)I-6β-iodomethyl-19-norcholesterol ((131)I-NP-59) scintigraphy. We present a case of a 29-year-old Han Chinese female patient with a history of hypercholestero...

BACKGROUND Increased morbidity and mortality associated with conventional glucocorticoid replacement therapy for primary adrenal insufficiency (primary AI; estimated prevalence 93-140/million), secondary AI (estimated prevalence, 150-280/million, respectively) or congenital adrenal hyperplasia (estimated prevalence, approximately 65/million) may be due to the inability of typical glucocorticoid...

objective(s): gallium-68 dota-dphe1-tyr3-octreotide (68ga-dotatoc) has been applied by several european centers for the treatment of a variety of human malignancies. nevertheless, definitive dosimetric data are yet unavailable. according to the society of nuclear medicine and molecular imaging, researchers are investigating the safety and efficacy of this radiotracer to meet food and drug admin...

We report the case of a 65 year old man with recent onset of insulin requiring diabetes mellitus, frequent attacks of anginal chest pain, paroxysmal hypertension poorly controlled with three medications, hyperlipidemia, and mild renal insufficiency. The patient was found to have pheochromocytoma of the left adrenal gland, resection of which resulted in total resolution of diabetes, hyperte...

Adrenal haemorrhage is a rare cause of adrenal crisis, which requires rapid diagnosis, prompt initiation of parenteral hydrocortisone and haemodynamic monitoring to avoid hypotensive crises. We herein describe a case of bilateral adrenal haemorrhage after hemicolectomy in a 93-year-old female with high-grade colonic adenocarcinoma. This patient's post-operative recovery was complicated by an ac...

Background: &nbsp;This study presents patient specific and organ dose estimation in computed tomography (CT) imaging of thorax directly from patient CT image using Monte Carlo simulation.&nbsp; Patient's CT image is considered as the patient specific phantom and the best representative of patient physical index in order to calculate specific organ dose. Materials and Methods: EGSnrc /BEAMnr...

we report the case of a 65 year old man with recent onset of insulin requiring diabetes mellitus, frequent attacks of anginal chest pain, paroxysmal hypertension poorly controlled with three medications, hyperlipidemia, and mild renal insufficiency. the patient was found to have pheochromocytoma of the left adrenal gland, resection of which resulted in total resolution of diabetes, hypertension...