Over the past decade, several technologies have emerged to access nucleic acid-tagged libraries and select the fittest compound within such libraries. This perspective focuses on recent development with PNA-tagged small molecules displayed on DNA templates for screening purposes and to probe the optimal geometry in multivalent interactions. WINSSINGER, Nicolas. DNA display of PNA-tagged ligands...

Knowledge of extinct herbivore community structuring is essential for assessing the wider ecological impacts of Quaternary extinctions and determining appropriate taxon substitutes for rewilding. Here, we demonstrate the potential for coprolite studies to progress beyond single-species diet reconstructions to resolving community-level detail. The moa (Aves: Dinornithiformes) of New Zealand are ...

In natural history collections throughout Europe, there are many old lion specimens of unknown origin. If these specimens can be shown to have originated from now-extinct populations their value would signi cantly increase, as would the value of the collections. Recently, a 200-year old mounted skeleton in the Zoological Museum Amsterdam has been identi ed as the extinct Cape lion Panthera le...

The variation of mitochondrial DNA (mtDNA) between modern humans and Neandertal sequences lie outside the mtDNA sequence variation within modern humans. This variation has led several researchers to conclude that Neandertals did not contribute to modern human DNA and are a separate species that went extinct in Europe. It is feasible that DNA can be retrieved from specimens that died thousands o...

to determine ancient seed species, 3250-3450 year-old charred seeds obtained from different iranian archaeological sites were studied using scanning electron microscopy (sem) and molecular analysis. sem analysis of ancient seeds revealed that the surface of the seeds was damaged. therefore, we could not accurately identify their species. molecular analysis on ancient specimens was done on diffe...

Extinct aurochs (Bos primigenius), accepted as the ancestor of domestic cattle, was one of the largest wild animals inhabiting Europe, Asia and North Africa. The gradual process of aurochs extinction finished in Poland in 1627, were the last recorded aurochs, a female, died. Some aspects of cattle domestication history and the distribution of aurochs genetic material among modern cattle breeds ...

Madagascar is well known for its diverse fauna and flora, being home to many species not found anywhere else in the world. However, its biodiversity in the recent past included a range of extinct enigmatic fauna, such as elephant birds, giant lemurs and dwarfed hippopotami. The 'Malagasy aardvark' (Plesiorycteropus) has remained one of Madagascar's least well-understood extinct species since it...