It is now almost a year since ADMET & DMPK launched. The current issue will be the final one for 2013. We are happy to report that it has been a very exciting year for the journal. In particular, we have published a range of articles, such as book reviews, original scientific papers, perspectives, opinions and mini reviews covering different areas of interest to the journal. This reflects the d...

Objectives: Psoriasis is a type of skin disease which accompanied with over production keratinocytes, itchiness, and scaly skin. In this study, an attempt was made to recognize naturally occurring phytocompounds from the plant Curcuma longa can be helpful in treating psoriasis using molecular docking techniques. Methods: The protein associated mechanism obtained data bank database, along retrie...

Plant Based Natural Products (PBNPs) have contributed to the development of many drugs for diverse indications. Worldwide interest in use plants based natural products has been growing, and its beneficial effects being rediscovered new drugs. Literature survey on indigenous traditional knowledge bestows ethnopharmacological potentials PBNPs, which inspired research drug discovery; further it pr...

ADMET Models, whether in silico or in vitro, are commonly used to 'profile' molecules, to identify potential liabilities or filter out molecules expected to have undesirable properties. While useful, this is the most basic application of such models. Here, we will show how models may be used to go 'beyond profiling' to guide key decisions in drug discovery. For example, selection of chemical se...