BACKGROUND Little is known about the association of kidney dysfunction and outcome in acute severe hypertension. This study aimed to measure the association between baseline chronic kidney disease (estimated glomerular filtration rate), acute kidney injury (AKI, decrease in estimated glomerular filtration rate > or =25% from baseline) and outcome in patients hospitalized with acute severe hyper...

A 52-year-old man acutely developed delirium and seizures associated with hypertension. MRI showed left hemispheric and brainstem lesions (figure). Profound agitation precluded visualization of the fundi, however an acute hypertensive retinopathy became apparent after pupillary dilatation (see figure). EKG (figure) and echocardiography showed left ventricular hypertrophy. With antihypertensive ...

Acute hypertension inhibits proximal tubule (PT) sodium reabsorption. The resultant increase in NaCl delivery to the macula densa suppresses renin release. We tested whether the sustained pressure-induced inhibition of PT sodium reabsorption requires a renin-mediated decrease in ANG II levels. Plasma ANG II concentration of anesthesized Sprague-Dawley rats was clamped by simultaneous infusion o...

drug induced acute kidney injury (aki) has been implicated in 8% to 60% of all cases of in-hospital aki and as such is a recognized source of significant morbidity and mortality. evaluation of incidence, risk factors, onset time, and outcome of  antibiotics' associated acute kidney injury. during one-year period, all patients who developed acute kidney injury during their hospital stay in the i...

BACKGROUND The long-term health consequences of acute bacterial gastroenteritis remain uncertain. We studied the risk of hypertension and reduced kidney function after an outbreak of acute gastroenteritis due to contamination of a regional drinking water supply with Escherichia coli O157:H7 and Campylobacter species. METHODS A total of 1958 adults with no known history of hypertension or kidn...

Necrosis, fibrinoid changes, and cellular infiltrations of pulmonary arterioles have been observed, among other alterations, in extreme pulmonary arterial hypertension. Whether these lesions are the cause or the effect of the high pressure, whether they are the consequence of spasm, or whether they are produced by some other mechanism such as hypersensitivity, remains to be established. Certain...

Background: The effects of vitamin D on the skeletal system, biological metabolism, and immune system function are well shown. Cholecalciferol (vitamin D2) ergocalciferol (vitamin) 2 major types D. Vitamin D3 deficiency is worldwide intoxication induced by it very rare. Conclusion: involved in calcium hemostasis. acute hypercalcemia blood pressure were established. Hypercalcemia can elevate pre...

Using data from the 2nd Gulf Registry of Acute Coronary Events (Gulf RACE-2) in 2008-09 we investigated the in-hospital complications and 1-year outcome of acute coronary syndrome (ACS) in patients with systemic hypertension from 6 Gulf countries. Of 7847 consecutive patients admitted with ACS, 3746 (47.7%) had hypertension. Hypertension was more prevalent in women, in Arabs than non-Arabs and ...

Traumatic brain injury (TBI) is the leading cause of death for children and young adults in the U.S. Current therapy is targeted towards treating hypertension in ICP after they occur. We investigated the change in the signal characteristics of three simultaneously recorded signals before and after an acute episode of intracranial hypertension. In this paper, we report statistical evidence of ch...