Acute generalised exanthematous pustulosis (AGEP) is a rare cutaneous eruption, most often caused by commonly used antibiotics. It is characterised by an acute onset of non-follicular sterile pustular rash and erythema within hours or days of drug exposure and usually resolves spontaneously within 1-2 weeks once the drug is discontinued. Haemodynamic involvement in the form of shock is rare. He...

Acute generalized exanthematous pustulosis (AGEP) is an uncommon eruption most often provoked by drugs, by acute infections with enteroviruses, or by mercury. It is characterized by acute, extensive formation of nonfollicular sterile pustules on erythematous background, fever, and peripheral blood leukocytosis. We present clinical and immunological data on four patients with this disease, which...

Acute generalized exanthematous pustulosis (AGEP) is characterized by acute onset of fever with a generalized erythematous pustular eruption. It seems that more than 90% of cases with AGEP are drug-induced [1]. The most frequently involved drugs are aminopenicillins, macrolides, antimycotic drugs, calcium channel blockers, carbamazepine, and paracetamol. We report a severe case of topical drug–...

Pustular allergic contact dermatitis (ACD) is rare, with reactions to the topical antibacterial nitrofurazone (1), isoconazole nitrate (2), topical minoxidil 2% (3), 1% fluorouracil (4), black rubber (5) and tricholoroethylene (6) having been reported. The clinical appearance of pustular ACD has been reported to comprise multiple small pustules, only 0.5–1mm in size, on a background of erythema...

This article addresses neutrophilic dermatoses, thus complementing the previous article (part I). The following dermatoses are introduced and discussed: subcorneal pustular dermatosis (Sneddon-Wilkinson disease), dermatitis cruris pustulosa et atrophicans, acute generalized exanthematous pustulosis, continuous Hallopeau acrodermatitis, palmoplantar pustulosis, infantile acropustulosis, Andrews'...