Xylene is a commonly used toxic volatile organic solvent. Diagnosis of acute xylene poisoning is limited by the lack of a readily available analytic assay. Methylhippuric acid, a metabolite of xylene excreted in the urine, is used for biomonitoring occupational exposures to xylene. We report two cases of acute occupational poisoning from xylene inhalation suggested by determination of high urin...

BACKGROUND The early prediction of the severity of acute pancreatitis still represents a challenge for clinicians. Experimental studies have revealed the generation of specific halogenated lipids, in particular oleic acid chlorohydrin, in the early stages of acute pancreatitis. We hypothesized that the levels of circulating oleic acid chlorohydrin might be a useful early prognostic biomarker in...

Paraquat is one of the most widely used herbicides in the world and is highly toxic to humans and animals. Respiratory failure as a result of lung injury is the most common cause of death from paraquat. In this study, we developed a lung metabolomic method by gas chromatography-mass spectrometry (GC-MS) to evaluate the effect of acute paraquat poisoning on rats. The acute paraquat poisoning gro...

osteoporosis is a silent epidemy of today's world, and is also a prevalent problem of health in iran. the role of nutrients such as ascorbic acid, a key antioxidant vitamin, in this disease has recently attracted researchers' attention. in this study, we studied the relation between plasma ascorbic acid concentration and bone mineral density (bmd) in women referring to jami clinic, te...

AIMS To investigate the relationship between adiposity and plasma free fatty acid levels and the influence of total plasma free fatty acid level on insulin sensitivity and β-cell function. METHODS An insulin sensitivity index, acute insulin response to glucose and a disposition index, derived from i.v. glucose tolerance minimal model analysis and total fasting plasma free fatty acid levels we...

ABSTRACT Introduction: Acute coronary syndrome (ACS) is a leading cause of death in Malaysia and worldwide. Besides, teh current treatment which involves prescription statins found to TEMPhas several side TEMPeffects on ACS patients. Those guided author introduce virgin coconut oil (VCO) as supplemental management ACS. However, its benefits not been widely tested humans. Methodology: dis study ...

Disturbances of acid-base balance and electrolyte abnormalities are commonly seen in patients with acute leukemia. Our study aimed at illuminating the probable pathogenetic mechanisms responsible for these disturbances in patients with acute leukemia admitted to our hospital. We studied 66 patients (24 men and 44 women) aged between 17 and 87 years old on their admission and prior to any therap...