نتایج جستجو برای: activation foci

تعداد نتایج: 442674  

1999
Finn Årup Nielsen

We apply machine learning techniques in the form of Gaussian mixture models to functional brain activation data. The dataset was extracted through the WWW interface to the BrainMap (Research Imaging Center, University of Texas Health Science Center at San Antonio) neuroimaging database. Modeling of the joint probability structure of activation foci and other database entries (e.g. behavioral do...

Journal: :Environmental Health Perspectives 1993
E J Matthews

Benzo[a]pyrene (BaP) induced significant morphological transformation of clone A31-1-13 BALB/c-3T3 cells without exogenous activation. Therefore, BaP was selected as a model to determine the internal consistency of detection of chemical-induced transformation. BaP induced a continuum of type I-III foci of different sizes, and the ratio of type I-III to type III foci/vessel was usually about 2-f...

Journal: :Development 1987
M H Johnson S J Pickering

The effect of dimethylsulphoxide (DMSO) on the organization of the microtubular system of the mouse oocyte has been examined. Exposure to DMSO causes the immediate appearance of multiple, cold-resistant microtubular asters associated with the foci of pericentriolar material (PCM) normally present in the oocyte. More prolonged exposure to DMSO leads to progressive disassembly of the spindle, and...

ژورنال: طلوع بهداشت یزد 2015
ثقفی پور, عابدین , جسری, ناهید , فخار, مهدی ,

Introduction: Zoonotic cutaneous leishmaniasis (ZCL) or rural cutaneous leishmaniasis is one of the most important health problems in different areas of Iran including Qom province. The aim of this study was to investigate the trend of CL incidence and also high-risk foci in Qom Province using geographical information system (GIS) method. Methods: Between 1994 and 2011, patient’s information ...

2011
Sergei Boichuk Liang Hu Kathleen Makielski Pier Paolo Pandolfi Ole V. Gjoerup

The promyelocytic leukemia protein (PML) is a tumor suppressor critical for formation of nuclear bodies (NBs) performing important functions in transcription, apoptosis, DNA repair and antiviral responses. Earlier studies demonstrated that simian virus 40 (SV40) initiates replication near PML NBs. Here we show that PML knockdown inhibits viral replication in vivo, thus indicating a positive rol...

Journal: :Journal of agricultural and food chemistry 2011
Ning-Ping Foo Hui Ou Yang Hsueh-Huei Chiu Hing-Yuen Chan Chii-Cherng Liao Chung-Keung Yu Ying-Jan Wang

Probiotics modulate immunity and inhibit colon carcinogenesis in experimental models, but these effects largely depend on the bacterial strain, and the precise mechanisms are not well understood. Therefore, we studied the effect of Bifidobacterium longum and/or Lactobacillus gasseri on the development of 1,2-dimethylhydrazine (DMH)-induced colonic precancerous lesions and tumors in mice whi...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه زنجان - دانشکده علوم انسانی و اجتماعی 1392

most specialists in the field of foreign language teachingconsiderreading skill as an interactive process between the reader’s prior knowledge and the text.accordingly, the activation of prior knowledge for an effective comprehension is very important. it is generally agreed that the pre-reading phase is the stage where this type of interaction and activation may be enhanced throughcertain stra...

Journal: :Journal of bacteriology 2009
Anja N J A Ridder Esther J de Jong Jan D H Jongbloed Oscar P Kuipers

The gram-positive bacterium Bacillus subtilis contains two minimal Tat translocases, TatAdCd and TatAyCy, which are each involved in the secretion of one or more specific protein substrates. We have investigated the subcellular localization of the TatA components by employing C-terminal green fluorescent protein (GFP) fusions and fluorescence microscopy. When expressed from a xylose-inducible p...

Journal: :Molecular cancer research : MCR 2007
V Ashutosh Rao Chiara Conti Josee Guirouilh-Barbat Asako Nakamura Ze-Hong Miao Sally L Davies Barbara Saccá Ian D Hickson Aaron Bensimon Yves Pommier

The Bloom syndrome helicase (BLM) is critical for genomic stability. A defect in BLM activity results in the cancer-predisposing Bloom syndrome (BS). Here, we report that BLM-deficient cell lines and primary fibroblasts display an endogenously activated DNA double-strand break checkpoint response with prominent levels of phosphorylated histone H2AX (gamma-H2AX), Chk2 (p(T68)Chk2), and ATM (p(S1...

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