نتایج جستجو برای: acrodermatitis enteropathica

تعداد نتایج: 475  

2008
Dierk Schleicher

We study the dynamics of iterated cosine maps E: z 7→ aez + be−z, with a, b ∈ C \ {0}. We show that the points which converge to ∞ under iteration are organized in the form of rays and, as in the exponential family, every escaping point is either on one of these rays or the landing point of a unique ray. Thus we get a complete classification of the escaping points of the cosine family, confirmi...

2015
Annie E. Schmidt Kristen E. Dybala Louis W. Botsford John M. Eadie Russell W. Bradley Jaime Jahncke Sébastien Descamps

With a rapidly changing climate, there is an increasing need to predict how species will respond to changes in the physical environment. One approach is to use historic data to estimate the past influence of environmental variation on important demographic parameters and then use these relationships to project the abundance of a population or species under future climate scenarios. However, as ...

2012
Jim Geiser Koen J. T. Venken Robert C. De Lisle Glen K. Andrews

Mutations in the human Zip4 gene cause acrodermatitis enteropathica, a rare, pseudo-dominant, lethal genetic disorder. We created a tamoxifen-inducible, enterocyte-specific knockout of this gene in mice which mimics this human disorder. We found that the enterocyte Zip4 gene in mice is essential throughout life, and loss-of-function of this gene rapidly leads to wasting and death unless mice ar...

Journal: :Biochemical Society transactions 2008
Glen K Andrews

The SLC39A (solute carrier 39A) [ZIP (Zrt-Irt-like protein)] family consists of 14 members which are thought to control zinc uptake into the cytoplasm. Among these, ZIP4 is known to be particularly important for zinc homoeostasis. Mutations in this gene cause acrodermatitis enteropathica, a rare recessive-lethal human genetic disorder. In the present paper, our studies of the regulation and fun...

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