Molecular sequence data show that the three species oDelphinium subg. Staphisagria (J. Hill) Peterm. form the sister clade to Aconitum L., Aconitella SpachConsolida (DC.) S.F. Gray, and all remaining species of Delphinium L. To account for this finding we resurrect Staphisagria J. Hill (1756). Names in Staphisagria are available for two of the species. We here make the required new combination ...

OBJECTIVE This study was performed to analyze the singledose toxicity of Aconitum kusnezoffii Reichb. pharmacopuncture (AKRP). METHODS All experiments were conducted at the Korea Testing & Research Institute (KTRI), an institute authorized to perform non-clinical studies, under the regulations of Good Laboratory Practice (GLP). Twenty (20) Sprague-Dawley rats were chosen for the pilot study. ...

Phylogenetic analyses were performed using multiple nuclear (ITS and ETS) and chloroplast regions (ndhF-trnL, psbA-trnH, psbD-trnT, and trnT-trnL) to test the monophyly of Aconitum subgen. Lycoctonum (Ranunculaceae) and reconstruct the phylogenetic relationships within the subgenus. The subgenus as currently circumscribed is revealed to be polyphyletic. To achieve its monophyly, sect. Galeata a...

Investigation and documentation of the status of medicinal plants and associated knowledge was conducted in village Dawarian, Neelum valley AJ&K. A total of 59 plant species were used for furteen (14) different categories of diseases. The medicinal plants were economically used in treating a certain ailments, such as skin diseases (10spp., 14.49%) followed by headache & fever, cough & flu (8spp...

Two new lycoctonine type C19-diterpenoid alkaloids, swatinine-A (1), and swatinine-B (2), along with four known C19-diterpenoid alkaloids, foresticine (3), neoline (4), delvestine (5), and chasmanine (6), were isolated from the aerial parts of the Aconitum laeve Royle. The structures of compounds 1 and 2 were deduced on the basis of spectroscopic techniques (EI-MS, HREI-MS, H NMR, C NMR, HMQC, ...

The immunomodulatory activity of diterpene alkaloids from Aconitum lycoctonum L. (Ranunculaceae family) was evaluated; the alkaloid components were extracted from plants grown wild in the Apennines near Parma (Northern Italy). The diterpene alkaloid lycoctonine evaluated by means of HPLC and IR techniques reaches its highest value in flowers, followed by stems, roots and leaves, while the maxim...

Aconitum species accumulate highly toxic diterpene alkaloids, which have attracted considerable interest because of their complex structure, interesting chemistry and noteworthy physiological effects. The authors carried out phytochemical analysis of two Aconitum species native to the Carpathian Basin, aiming the isolation of diterpene alkaloids. The multistep chromatographic purification of th...

Lipo-alkaloid is a kind of C19-norditerpenoid alkaloid usually found in Aconitum species. Structurally, they contain an aconitane skeleton and one or two fatty acid moieties of 3-25 carbon chains with 1-6 unsaturated degrees. Analysis of the lipo-alkaloids in roots of Aconitum carmichaelii resulted in the isolation of six known pure lipo-alkaloids (A1-A6) and a lipo-alkaloid mixture (A7). The m...