The genus Achillea L. includes more than 100 species and is a polyploid complex of di-, tetra-, hexa- and octaploids, individuals.

The aerial parts of Achillea setacea afforded, in addition of a rare monoterpene triol and 12 known sesquiterpene lactones, a new guaianolide containing an endoperoxide ring. Its structure was elucidated by spectral methods.

Lipoarabinomannan (LAM) is a component of the mycobacterial surface which has been associated with a variety of deleterious effects on immune system function. Despite the importance of LAM to the pathogenesis of mycobacterial infection, there is no information available on its fate in vivo. In this study, we determined the pharmacokinetics and tissue distribution of exogenously administered LAM...

The anti-inflammatory activity of Achillea and Ruscus extracts was studied in comparison with diclofenac sodium topical gel (diclosal Emulgel), using the carrageenan induced paw edema model in Albino rats. Gel formulation was prepared containing 6% of each extract in gel base, namely sodium carboxymethylcellulose (NaCMC). The kinetics of drug release from the prepared formulation was studied se...

We studied the cognitive improving and cerebral protective constituents in the roots of Polygala tenuifolia Willdenow, a well-known Chinese traditional medicine prescribed for amnesia, neurasthenia, palpitation, noctural emission and insomnia. Tenuifoliside B (1), which is one of the acylated oligosaccharides in the roots of P. tenuifolia, showed the cerebral protective effect on potassium cyan...

The aim of this work was to study the chemical composition, antioxidant and antibacterial properties of Achillea distans Waldst. et Kit. subsp. distans and Achillea distans Waldst. et Kit. subsp. alpina Rochel, from the Rodna Mountains (Romania). The identification and quantification of major phenolic compounds was performed by a HPLC-MS method. The total polyphenolic and flavonoid content was ...

The active parts of 11 medicinal plants were analyzed for physico-chemical evaluation, phytochemical determination and antioxidant activity. The physico-chemical evaluation revealed that highest water soluble extractive was from Origanum vulgare (38%), highest chloroform extractive was from Psoralea corylifolia (21%); highest ethanolic extractive was that of Acorus calamus (11%) and the highest...

In this study, a new chromosome number for Iranian yarrow (Achillea millefolium L.) accessions was reported. Cytological analyses on four Achillea millefolium accessions, indicated that two accessions were diploids (2n=2x=18) and two tetraploids (2n=4x=36). Cluster analysis based on chromosomal characteristics and karyotype asymmetry, categorized the four accessions separated into two groups. I...