H uman leukocyte antigen (HLA) matching is critically important for successful hematopoietic progenitor cell (HPC) transplantation because the rates of engraftment and transplant outcomes are strongly influenced by the degree of match. This is largely because HLA antigens are expressed on immature pluripotent stem cells. In contrast, ABO incompatibility is not a barrier to successful HPC transp...

Distribution of A, B, AB, 0 and Rh blood groups was determined in the residents of Bahawalpur through a survey of 2036 individuals. The distribution was B, 35.26%, 0, 26.23%, A, 25.69%, and AB, 12.82%. Nintyeight percent individuals were Rh positive and 2% negative. The results when classified according to the sex showed females to be twice more Rh-negative than males and none of the 160 AB mal...

von Willebrand factor (vWF) is synthesized exclusively by endothelial cells and megakaryocytes, and stored in the intracellular granules or constitutively secreted into plasma. ABO blood group antigens are covalently associated with asparagine-linked sugar chains of plasma vWF. The effect of ABO-mismatched bone marrow transplantation (BMT) or blood stem cell transplantation (BSCT) on the expres...

OBJECTIVE Aim of our study was to evaluate distribution of ABO and Rh blood type groups in children after hip surgery regarding transfusion administration and fever presence. METHODS Four types of ABO blood groups (A; B; AB; O) and 2 types of Rh blood groups (Rh+; Rh-) were evaluated in group with administered transfusion (tr+) and without given transfusion (tr-); and in group with fever (fev...

Introduction The antigens of the ABO blood group system (A, B and H determinants, respectively) are complex carbohydrate molecules on the extracellular surface of red blood cells1. However, besides being expressed on red blood cells, ABO antigens are also strongly expressed on the surface of a variety of human cells and tissues, including the epithelium, sensory neurones, platelets, and the vas...

Antigens of the ABO blood group system (i.e., A, B, and H antigens) and Rhesus factor were discovered more than one century ago by karl & steiner [1,2] who is considering the father of transfusion medicine, and with this discovery he enabling physicians to transfuse blood without endangering the patient′s life. The ABO antigens are defined by carbohydrate moieties on the extracellular surface o...

Hemolytic disease of newborn (HDN) is caused by the emergence of inappropriate antibodies against fetal blood antigens, which includes ABO and Rh blood group incompatibility. This study investigated the association between prenatal blood group antibody titer and HDN to provide a theoretic basis for clinical practice. ABO and Rh blood group of 7894 pregnant women and their husbands were screened...

Association between certain systemic diseases and ABO blood group is a well known fact. The purpose of this study was to determine whether there is any association between periodontal disease and ABO blood groups. A cross sectional study was carried-out on 200 subjects who were randomly selected from individuals referred for periodontal treatment. The study subjects were segregated into healthy...

Since the first link between blood type and cancer was described in 1953, numerous studies have sought to determine whether the histoblood ABO group is associated with tumorigenesis. In 2009, the first significant association between a SNP located within the ABO glycosyltransferase gene and increased risk of pancreatic cancer was reported. Here, we describe the history and possible functions of...