Insulin degradation within isolated rat liver endosomes was studied in vitro with the aid of three 125I-insulin isomers specifically labelled at tyrosine (A14, B16 and B26). Chloroquine and 1,10-phenanthroline were used to minimize insulin proteolysis during endosome preparation, whereas the manipulation of endosomal processing of insulin in vitro by Co2+ ions (to activate) and 1,10-phenanthrol...

Fermat’s little theorem says for prime p that ap−1 ≡ 1 mod p for all a 6≡ 0 mod p. A naive extension of this to a composite modulus n ≥ 2 would be: for a 6≡ 0 mod n, an−1 ≡ 1 mod n. Let’s call this “Fermat’s little congruence.” It may or may not be true. When n is prime, it is true for all a 6≡ 0 mod n. But when n is composite it usually has many counterexamples. Example 1.1. When n = 15, the t...

Assembly of the poxvirus immature virion (IV) membrane is a poorly understood event that occurs within the cytoplasm. At least eight viral proteins participate in formation of the viral membrane. Of these, A14, A17, and D13 are structural components whereas A6, A11, F10, H7, and L2 participate in membrane biogenesis. L2, the object of this study, is conserved in all chordopoxviruses, expressed ...

In 1969, a forgettable Hollywood movie parodied the information overload that tourists experience when they visit several countries in the shortest time possible. Thirty years later, scientists who are interested in chemokines also find their heads spinning in response to a seemingly endless and rapid parade of newly discovered chemokines and receptors. In this issue, Struyf and colleagues (pag...

The research objective was to determine the growth and production of fifth generation mutant soybean (M5) at Lampahan Bener Meriah University Farm. This study used a non-factorial randomized block design (RBD) with three replications, where four genotypes Kipas Merah mutants were tested compared (their parents) Grobogan variety (large seeds). variables observed plant height, number branches, pr...

Instruktur merupakan unsur terpenting yang harus ada pada sebuah kegiatan belajar dalam pelatihan kerja. Seorang instruktur di suatu program kerja haruslah benar-benar professional dan berkualitas. Kunci utama dipunyai oleh setiap ialah kompetensi. Perlu dilakukan pemeringkatan kompetensi BBPVP Medan. Pemeringkatan ini bertujuan untuk meningkatkan kinerja semangat dari masing-masing tersebut. B...