نتایج جستجو برای: a terreus 23
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توانایی قارچ رشته ای acremonium strictum ptcc 5282 در ایجاد تغییرات زیستی بر استروئیدهای دارویی پروژسترون ، هیدروکورتیزون ، پردنیزولون و همچنین قارچ سیاه aspergillus terreus ptcc5283 بر ترکیب حدواسط استروئیدی آندروستن دیون در این تحقیق مورد بررسی قرار گرفته است.
The fungal metabolite (+)-geodin [systematic name: (2R)-methyl 5,7-dichloro-4-hydroxy-6'-methoxy-6-methyl-3,4'-dioxospiro[benzofuran-2,1'-cyclohexa-2',5'-diene]-2'-carboxylate], C(17)H(12)Cl(2)O(7), was isolated from Aspergillus terreus. The crystal structure contains two independent molecules in the asymmetric unit. Molecules denoted 1 interact through O-H...O hydrogen bonds creating chains of...
In the process development of lovastatin using Aspergillus terreus DRCC 152 in solid state fermentation, we have isolated a new butyrolactone-IV (3) along with the previously reported butyrolactone-I (1) and butyrolactone-II (2) produced under submerged conditions. The structure of compound 3 has been characterized as 3-hydroxy-5-[2-(1-hydroxy-1-methylethyl)-2(R)-2,3-dihydro-benzo[b]furan- 5 yl...
We compared the activity of four doses of micafungin (FK463) with that of amphotericin B, liposomal amphotericin B and itraconazole in a murine model of disseminated aspergillosis. Temporarily neutropenic mice were infected with a lethal dose of either an itraconazole-resistant Aspergillus fumigatus isolate or Aspergillus terreus, a species that is less susceptible to amphotericin B. Treatment ...
Acinetobacter baumannii is a bacterial pathogen, associated with hospital and community acquired infections. It one of the most common, opportunistic, serious multidrug resistant bacteria (MDR). considered global problem. The use natural compounds such as fungal metabolites an alternative to antibiotics being explored overcome issue antimicrobial resistance. Among fifty spp. isolated from diffe...
Cystic Fibrosis (CF) is the most common inherited life shortening condition affecting Caucasians. CF is characterised by mutations in the CF transmembrane conductance regulator (CFTR) gene, which codes for an ATP-driven pump that transports sodium and chloride ions across epithelial surfaces [1]. CF is a multiple organ disease; however up to 95% of morbidity and mortality is due to pulmonary in...
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