Abstract Background Of late, periarticular analgesic injection (PAI) has become a common alternative treatment for pain following total hip arthroplasty (THA). However, the systemic effects of PAI containing corticosteroids in patients subjected to THA have not been investigated. This study evaluated efficacy and corticosteroid THA. Methods single-center, retrospective cohort enrolled undergoin...

BACKGROUND Patient-reported scoring systems have recently been used after surgical procedures. The purpose of this prospective study was to evaluate the patient-reported outcomes of femoral osteotomy and total hip arthroplasty (THA) for osteonecrosis of the femoral head (ONFH). METHODS Forty-two symptomatic ONFH patients with asymptomatic contralateral hip underwent either transtrochanteric a...

Metal-on-metal (MoM) total hip arthroplasty (THA) can be associated with adverse metal reactions, including pseudotumors. This case report describes a 58-year-old female with an MoM THA-related pseudotumor that caused unilateral leg edema from compression of her external iliac vein. After thorough preoperative workup to rule out infection and deep vein thrombosis and consultation with a vascula...

Revision total hip arthroplasty (THA) is associated with greater blood loss than primary THA. Jehovah's Witnesses will not accept transfusions of blood or blood products and are thus at an increased risk for complications due to perioperative anemia. The purpose of this study was to report the clinical outcomes, radiographic outcomes, morbidity, and mortality of Jehovah's Witnesses who were med...

Tetrahydroaminoacridine (THA) is a centrally active anticholinesterase that also interacts with neuronal K+ and Na+ channels and cardiac Ca2+ channels. The effects of THA on neuronal voltage-dependent Ca2+ channels are not known. We tested the effects of THA (25 nM-250 microM) on the Ca2+ current components of acutely dissociated rat nodose ganglion and dorsal root ganglion (DRG) neurons using ...

subchondral insufficiency fracture of the femoral head (siffh) is characterized by acute onset hip pain without overt trauma. it appears as a low intensity band with bone marrow edema on t1-weighted mri. the most common course of treatment is protected weight bearing for a period of several weeks. total hip arthroplasty (tha) has been commonly used if the patient does not respond to the initial...

BACKGROUND Both minimally invasive surgery (MIS) and computer-assisted surgery (CAS) for total hip arthroplasty (THA) have gained popularity in recent years. We conducted a qualitative and systematic review to assess the effectiveness of MIS, CAS and computer-assisted MIS for THA. METHODS An extensive computerised literature search of PubMed, Medline, Embase and OVIDSP was conducted. Both ran...

OBJECTIVE To assess the efficacy of a single intra-articular injection of triamcinolone hexacetonide (THA) in knee osteoarthritis (OA) and examine factors which may relate to treatment efficacy. METHODS Eighty four patients with clinical and radiographic evidence of knee OA were recruited and randomly allocated to receive either THA (20 mg in 1 ml) or placebo (0.9% normal saline, 1 ml). Follo...

BACKGROUND Rates of hip arthroscopy have been on an exponential rise. The purpose of this study was to evaluate the rate and timing of subsequent total hip arthroplasty (THA) after hip arthroscopy and identify if rates of THA differed based on age, diagnosis of osteoarthritis, or arthroscopic procedure performed. METHODS The Humana administrative claims data set was reviewed from 2007 to 2014...

BACKGROUND Natural products represent an important source for agents of cancer prevention and cancer treatment. More than 60% of conventional anticancer drugs are derived from natural sources, particularly from plant-derived materials. In this study, 2α, 3α, 19β, 23β-tetrahydroxyurs-12-en-28-oic acid (THA), a novel triterpenoid from the leaves of Sinojackia sarcocarpa, was isolated, and its ant...